Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457239 | 1.00 | MAPT (0.47) | MAPTTRPA1ATMHTR1BPOLB | |
| SCHEMBL3889703 | 0.89 | MAPT (0.46) | MAPTTRPA1ATMHTR1BPOLB | |
| SCHEMBL457237 | 0.84 | MAPT (0.48) | MAPTTRPA1ATMHTR1BPOLB | |
| SCHEMBL29703714 | 0.84 | MAPT (0.48) | MAPTTRPA1ATMHTR1BPOLB | |
| SCHEMBL27764640 | 0.83 | TRPA1 (0.52) | MAPTTRPA1ATMPOLBLMNA | |
| SCHEMBL3900215 | 0.82 | MAPT (0.44) | MAPTTRPA1ATMHTR1BPOLB | |
| SCHEMBL31629381 | 0.82 | TRPA1 (0.34) | MAPTTRPA1ATM | |
| SCHEMBL5892479 | 0.82 | TRPA1 (0.34) | MAPTTRPA1ATM | |
| SCHEMBL30366069 | 0.81 | TSHR (0.45) | LMNARAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL350128 | 0.81 | TSHR (0.45) | LMNARAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239562-A | Method for synthesizing doxepin hydrochloride by taking benzofuranone as raw material | 江苏师范大学 | 2023-06-09 | — | — | CN | claimed |
| CN-113429533-B | Preparation and degradation methods of hot-melt phenolic resin and composite material thereof | 中国地质大学（北京） | 2023-02-03 | — | — | CN | claimed |
| CN-116239562-A | Method for synthesizing doxepin hydrochloride by taking benzofuranone as raw material | 江苏师范大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-112321628-B | Preparation method of beta-dimethylphenyl silicon substituted organic nitrile compound | 湖北工程学院 | 2023-04-28 | — | — | CN | disclosed |
| CN-111995635-B | Method for preparing organosilicon compound by catalyzing chitosan loaded copper film material | 湖北工程学院 | 2023-04-25 | — | — | CN | disclosed |
| CN-113429533-B | Preparation and degradation methods of hot-melt phenolic resin and composite material thereof | 中国地质大学（北京） | 2023-02-03 | — | — | CN | disclosed |