SCHEMBL4572808

SCHEMBL4572808

CNC(=O)N(CCO)CCO

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
ALDH2 P05091 1/20 0.38
ROCK2 O75116 1/20 0.35
MAPT P10636 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
NQO1 P15559 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11586574 0.84 KEAP1 (0.34)
SCHEMBL43323 0.79 CA12 (0.48) ALDH1A1ALDH2CA12CA1CA2
SCHEMBL9760273 0.79 ROCK2 (0.35) ROCK2MAPTNQO1
SCHEMBL11069835 0.78
SCHEMBL692070 0.77
SCHEMBL4503702 0.75 ALDH1A1 (0.51) ALDH1A1ROCK2
SCHEMBL4572776 0.75 ALDH1A1 (0.40) ALDH1A1ALDH2MAPTCA12CA1
SCHEMBL4580304 0.75
SCHEMBL8622931 0.75
SCHEMBL5695570 0.75 CA12 (0.52) ALDH1A1ALDH2MAPTCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080081052-A1 Topical compositions containing solubilized allantoin and related methods ZHANG JERRY 2008-04-03 US disclosed
US-20080057002-A1 Non-aqueous compositions containing urea and allantoin and methods for preparing same ZHANG JERRY 2008-03-06 US disclosed
US-20070172436-A1 Nonaqueous ascorbic acid compositions and methods for preparing same ZHANG JERRY 2007-07-26 US disclosed