Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448504 | 0.78 | KDM1A (0.54) | KDM1AKMT2ASLC6A4SLC6A2OPRM1 | |
| SCHEMBL31557718 | 0.77 | OPRM1 (0.64) | KDM1AKMT2ASLC6A4SLC6A2OPRM1 | |
| SCHEMBL3159689 | 0.77 | KDM1A (0.57) | KDM1AKMT2ASLC6A4SLC6A2OPRM1 | |
| Hydrochloric Acid SCHEMBL18742400 | 0.76 | KDM1A (0.56) | KDM1AKMT2ASLC6A4SLC6A2OPRM1 | |
| SCHEMBL6841581 | 0.74 | KDM1A (0.54) | KDM1AKMT2ASLC6A4SLC6A2OPRM1 | |
| SCHEMBL1660644 | 0.74 | OPRM1 (0.61) | KDM1AKMT2ASLC6A4SLC6A2OPRM1 | |
| SCHEMBL6446868 | 0.74 | SLC6A4 (0.50) | KDM1AKMT2ASLC6A4SLC6A2OPRM1 | |
| SCHEMBL22369878 | 0.74 | KDM1A (0.54) | KDM1AKMT2ASLC6A4OPRD1ACHE | |
| SCHEMBL17982834 | 0.74 | KDM1A (0.54) | KDM1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6831189 | 0.74 | OPRM1 (0.61) | KDM1AKMT2ASLC6A4SLC6A2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |