Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.47 |
| ▸ | CHRNG | P07510 | 1/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446868 | 0.91 | SLC6A4 (0.50) | KDM1AOPRD1KMT2ACA1CA2 | |
| SCHEMBL28001878 | 0.88 | ADRB1 (0.49) | KDM1AOPRD1KMT2ACA1CA2 | |
| SCHEMBL28367891 | 0.82 | OPRD1 (0.41) | KDM1AOPRD1KMT2AKCNH2SLC6A4 | |
| SCHEMBL8842426 | 0.81 | SLC6A2 (0.48) | KDM1AOPRD1KMT2ACA1CA2 | |
| SCHEMBL13959797 | 0.80 | NPY1R (0.46) | KDM1AOPRD1KCNH2 | |
| SCHEMBL12477851 | 0.78 | LMNA (0.51) | KMT2AOPRM1OPRL1 | |
| SCHEMBL31557718 | 0.78 | OPRM1 (0.64) | KDM1AOPRD1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL3159689 | 0.78 | KDM1A (0.57) | KDM1AOPRD1KMT2ACA1CA2 | |
| SCHEMBL4573102 | 0.78 | KDM1A (0.53) | KDM1AOPRD1KMT2ACA1CA2 | |
| SCHEMBL28425450 | 0.78 | CA1 (0.52) | KDM1AOPRD1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160271160-A1 | HCV POLYMERASE INHIBITORS | MEDIVIR AB (SE) | 2016-09-22 | — | — | US | disclosed |
| EP-1527077-A2 | PYRROLOPYRAZINES AS KINASE INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2005-05-04 | — | — | EP | disclosed |
| WO-2004016614-A2 | PYRROLOPYRAZINES AS KINASE INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2004-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160271160-A1 | HCV POLYMERASE INHIBITORS | POLI, POLB, POLL | KDM1A 3222/4885OPRD1 801/4885KMT2A 2713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.