Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 16/20 | 0.54 |
| ▸ | DRD2 | P14416 | 5/20 | 0.54 |
| ▸ | DRD3 | P35462 | 5/20 | 0.54 |
| ▸ | CDK4 | P11802 | 3/20 | 0.49 |
| ▸ | CCND1 | P24385 | 3/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4850347 | 0.95 | HTR1A (0.55) | HTR1ADRD2DRD3CDK4CCND1 | |
| SCHEMBL7004582 | 0.83 | HPGD (0.50) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL377396 | 0.78 | HTR1A (0.51) | HTR1ADRD2DRD3CDK4CCND1 | |
| SCHEMBL7005388 | 0.78 | HPGD (0.55) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL10637456 | 0.77 | HTR1A (0.45) | HTR1ADRD2DRD3CDK4CCND1 | |
| SCHEMBL97632 | 0.75 | HTR3A (0.48) | HTR1ADRD2DRD3 | |
| SCHEMBL9309089 | 0.75 | USP2 (0.43) | HTR1ADRD2DRD3CDK4CCND1 | |
| SCHEMBL7351006 | 0.75 | HTR1A (0.65) | HTR1ADRD2DRD3 | |
| SCHEMBL8616515 | 0.74 | HTR1A (0.42) | HTR1ADRD2DRD3CDK4CCND1 | |
| SCHEMBL7353227 | 0.74 | HTR1A (0.64) | HTR1ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050207-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANABOLIC AGENTS FOR LIVESTOCK ANIMALS | PFIZER LIMITED (GB) | 2008-05-02 | — | — | WO | claimed |
| EP-3190114-A1 | PROCESS FOR MAKING A CRYSTALLINE ZILPATEROL SALT | Intervet International B.V. (NL) | 2017-07-12 | — | — | EP | disclosed |
| WO-2008050207-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANABOLIC AGENTS FOR LIVESTOCK ANIMALS | PFIZER LIMITED (GB) | 2008-05-02 | — | — | WO | disclosed |