Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.50 |
| ▸ | HTR3B | O95264 | 3/20 | 0.50 |
| ▸ | HTR3A | P46098 | 3/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541552 | 0.86 | ADRB1 (0.50) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| SCHEMBL4538749 | 0.83 | ADRB1 (0.51) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| SCHEMBL8099474 | 0.83 | ADRB1 (0.47) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| SCHEMBL26472636 | 0.82 | KMT2A (0.55) | ALDH1A1KDM4ELMNASIRT6 | |
| SCHEMBL12088780 | 0.80 | ADRB1 (0.58) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| SCHEMBL20424733 | 0.79 | KDM4E (0.59) | ALDH1A1KDM4ELMNA | |
| SCHEMBL270283 | 0.79 | ADRB1 (0.62) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| SCHEMBL15577925 | 0.78 | MAPT (0.52) | ALDH1A1LMNA | |
| SCHEMBL27901112 | 0.77 | ADRB1 (0.44) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| Trifluoroacetic Acid SCHEMBL6336692 | 0.76 | ADRB1 (0.69) | ALDH1A1USP2TSHRHSD17B10ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |