SCHEMBL270283

SCHEMBL270283

CC(C)(C)c1ccc(N2CCNCC2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 9/20 0.62
HTR3A P46098 4/20 0.57
HTR3E A5X5Y0 3/20 0.57
HTR3B O95264 3/20 0.57
HTR3D Q70Z44 3/20 0.57
HTR3C Q8WXA8 3/20 0.57
SIGMAR1 Q99720 3/20 0.57
ADRB2 P07550 1/20 0.52
NCF1 P14598 1/20 0.52
PLD1 Q13393 1/20 0.52
HPGD P15428 1/20 0.51
HTR1A P08908 1/20 0.51
LTA4H P09960 3/20 0.49
ALDH1A1 P00352 2/20 0.49
KDM4E B2RXH2 1/20 0.49
LMNA P02545 1/20 0.49
SIRT6 Q8N6T7 1/20 0.49
HSD11B1 P28845 1/20 0.46
USP2 O75604 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5229788 0.93 ADRB1 (0.55) ADRB1HTR3AHTR3EHTR3BHTR3D
Hydrochloric Acid SCHEMBL381874 0.91 ADRB1 (0.53) ADRB1HTR3AHTR3EHTR3BHTR3D
SCHEMBL23772144 0.89 ADRB1 (0.48) ADRB1HTR3AHTR3EHTR3BHTR3D
Tert-Butyl Formate SCHEMBL28331831 0.86 ADRB1 (0.47) ADRB1HTR3AHTR3EHTR3BHTR3D
SCHEMBL20178041 0.85 HSD11B1 (0.57) ALDH1A1KDM4ELMNAHSD11B1USP2
SCHEMBL12088780 0.85 ADRB1 (0.58) ADRB1HTR3AHTR3EHTR3BHTR3D
SCHEMBL18308985 0.84 L3MBTL3 (0.53) ADRB1HTR3AHTR3EHTR3BHTR3D
SCHEMBL24123997 0.83 CYP2D6 (0.63) ADRB1HTR3AHTR3EHTR3BHTR3D
SCHEMBL5570604 0.82 ADRB1 (0.77) ADRB1HTR3AHTR3EHTR3BHTR3D
SCHEMBL14384537 0.82 ADRB1 (0.55) ADRB1HTR3AHTR3EHTR3BHTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059950-A Compounds with proteasome agonistic activity, preparation method and application thereof 浙大城市学院 2026-05-19 CN disclosed
EP-3628045-B1 COMPOUNDS UNIV SHEFFIELD (GB) 2024-07-03 EP disclosed
EP-4371982-A2 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS RQX Pharmaceuticals, Inc. (US) 2024-05-22 EP disclosed
EP-3583096-B1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS RQX PHARMACEUTICALS INC (US) 2024-03-27 EP disclosed
US-20230382909-A1 BICYCLIC COMPOUNDS ALIGOS THERAPEUTICS, INC. 2023-11-30 US disclosed
US-20230374008-A1 BICYCLIC COMPOUNDS ALIGOS THERAPEUTICS, INC. 2023-11-23 US disclosed
US-20230303570-A1 KINASE INHIBITORS AND USES THEREOF ABM THERAPEUTICS CORP (US) 2023-09-28 US disclosed
US-20230303570-A1 KINASE INHIBITORS AND USES THEREOF ABM THERAPEUTICS CORP (US) 2023-09-28 US disclosed
US-11701370-B2 Phosphonium ion channel blockers and methods for use Nocion Therapeutics, Inc. (US) 2023-07-18 US disclosed
US-11701370-B2 Phosphonium ion channel blockers and methods for use Nocion Therapeutics, Inc. (US) 2023-07-18 US disclosed
EP-0974573-A1 PHENYLPROPENONE COMPOUNDS AND MEDICINES CONTAINING THE SAME Kabushiki Kaisha Yakult Honsha (JP) 2000-01-26 EP disclosed
EP-0278008-B1 TAURINE TYPE COMPOUNDS TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1993-01-20 EP disclosed
EP-0327912-B1 N,N-DISUBSTITUTED PIPERAZINES BASF Aktiengesellschaft (DE) 1992-04-08 EP disclosed
US-4935426-A FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1990-06-19 US disclosed
US-4870078-A TAURINE-TYPE COMPOUNDS TAIHO PHARMACEUTICAL CO., LTD. (JP) 1989-09-26 US disclosed
EP-0327912-A1 N,N-disubstituted piperazines BASF Aktiengesellschaft (DE) 1989-08-16 EP disclosed
EP-0278008-A1 TAURINE TYPE COMPOUNDS TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1988-08-17 EP disclosed
EP-0114374-B1 SUBSTITUTED 4-AMINOMETHYLENE CHROMANS OR CHROMENES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES BAYER AG (DE) 1986-07-23 EP disclosed
US-4563458-A CIRCULATORY SYSTEM DISORDERS BAYER AKTIENGESELLSCHAFT (DE) 1986-01-07 US disclosed
EP-0114374-A1 Substituted 4-aminomethylene chromans or chromenes, process for their preparation and their use in medicines BAYER AG (DE) 1984-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303570-A1 KINASE INHIBITORS AND USES THEREOF ERBB2, ERBB3, ERBB4 ADRB1 1589/4885HTR3A 916/4885HTR3E 836/4885
US-20230382909-A1 BICYCLIC COMPOUNDS SLC10A1, PKD1, CYP11B2 ADRB1 853/4885HTR3A 2220/4885HTR3E 3034/4885
US-20230374008-A1 BICYCLIC COMPOUNDS SLC10A1, PKD1, CYP11B2 ADRB1 853/4885HTR3A 2220/4885HTR3E 3034/4885
US-11701370-B2 Phosphonium ion channel blockers and methods for use TRPV1, TRPV5, TRPA1 ADRB1 423/4885HTR3A 2526/4885HTR3E 2867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.