Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5755068 | 0.87 | TSHR (0.56) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL1989382 | 0.87 | TSHR (0.56) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL1524101 | 0.85 | TSHR (0.67) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL1524411 | 0.85 | TSHR (0.67) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL1524098 | 0.85 | TSHR (0.67) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL6941005 | 0.85 | TSHR (0.67) | TSHRCA1CA2CA7CA9 | |
| Ammonia Solution, Strong SCHEMBL7095980 | 0.83 | TSHR (0.64) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL798003 | 0.81 | TSHR (0.61) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL2674841 | 0.81 | TSHR (0.61) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL20953940 | 0.81 | TSHR (0.61) | TSHRCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319084-B2 | Catalysts containing N-pyrrolyl substituted nitrogen donors | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-01-15 | — | — | US | disclosed |
| US-20060178490-A1 | Catalysts containing N-pyrrolyl substituted nitrogen donors | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-08-10 | — | — | US | disclosed |
| US-7056996-B2 | Productivity catalysts and microstructure control | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-06-06 | — | — | US | disclosed |
| US-6946532-B2 | Catalysts containing per-ortho aryl substituted aryl or heteroaryl substituted nitrogen donors | EASTMAN CHEMICAL COMPANY (US) | 2005-09-20 | — | — | US | disclosed |
| US-20050090381-A1 | Catalysts containing per-ortho aryl substituted aryl or heteroaryl substituted nitrogen donors | EASTMAN CHEMICAL COMPANY (US) | 2005-04-28 | — | — | US | disclosed |
| US-20050090630-A1 | Supported group 8-10 transition metal olefin polymerization catalysts | EASTMAN CHEMICAL COMPANY (US) | 2005-04-28 | — | — | US | disclosed |
| US-20050054856-A1 | Catalysts containing N-pyrrolyl substituted nitrogen donors | EASTMAN CHEMICAL COMPANY (US) | 2005-03-10 | — | — | US | disclosed |
| US-6844446-B2 | Catalysts containing per-ortho aryl substituted aryl or heteroaryl substituted nitrogen donors | EASTMAN CHEMICAL COMPANY (US) | 2005-01-18 | — | — | US | disclosed |
| US-6844404-B2 | Catalyst compositions for the polymerization of olefins | EASTMAN CHEMICAL COMPANY (US) | 2005-01-18 | — | — | US | disclosed |
| US-6825356-B2 | REMAINING DONOR ATOMS OF THE LIGAND ARE SELECTED FROM THE GROUP CONSISTING OF C, N, P, AS, O, S, AND SE | EASTMAN CHEMICAL COMPANY | 2004-11-30 | — | — | US | disclosed |
| WO-2001083571-A2 | CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS | EASTMAN CHEMICAL COMPANY (US) | 2001-11-08 | — | — | WO | disclosed |
| US-6303720-B1 | E.G., NICKEL COMPLEX OF 2,3-BIS(2,6-DIMETHYLPHENYLIMINO)-(1,4)-DITHIANE | EASTMAN CHEMICAL COMPANY | 2001-10-16 | — | — | US | disclosed |
| US-20010025007-A1 | Catalyst compositions for the polymerization of olefins | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-09-27 | — | — | US | disclosed |
| US-6281303-B1 | TRANSITION METAL COMPLEX | EASTMAN CHEMICAL COMPANY | 2001-08-28 | — | — | US | disclosed |
| US-6200925-B1 | AS POLYMERIZATION CATALYST | EASTMAN CHEMICAL COMPANY | 2001-03-13 | — | — | US | disclosed |
| US-6174976-B1 | BATCH OR CONTINUOUS PROCESSING FOR OLEFIN POLYMERIZATION WITH NICKEL CATALYSTS | EASTMAN CHEMICAL COMPANY | 2001-01-16 | — | — | US | disclosed |
| WO-2000050470-A2 | CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS | EASTMAN CHEMICAL COMPANY (US) | 2000-08-31 | — | — | WO | disclosed |
| US-6103658-A | Olefin polymerization catalysts containing group 8-10 transition metals, processes employing such catalysts and polymers obtained therefrom | EASTMAN CHEMICAL COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| EP-0966490-A2 | CATALYST COMPOSITIONS FOR THE POLYMERIZATION OF OLEFINS | EASTMAN CHEMICAL COMPANY (US) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998040420-A2 | CATALYST COMPOSITIONS FOR THE POLYMERIZATION OF OLEFINS | EASTMAN CHEMICAL COMPANY (US) | 1998-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178490-A1 | Catalysts containing N-pyrrolyl substituted nitrogen donors | NCL, NSFL1C, NCLN | TSHR 4856/4885CA1 4579/4885CA2 4776/4885 |
| US-20050054856-A1 | Catalysts containing N-pyrrolyl substituted nitrogen donors | NCL, NSFL1C, NCLN | TSHR 4856/4885CA1 4579/4885CA2 4776/4885 |
| US-20050090381-A1 | Catalysts containing per-ortho aryl substituted aryl or heteroaryl substituted nitrogen donors | NOX3, AHR, POF1B | TSHR 4248/4885CA1 4624/4885CA2 4311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.