SCHEMBL5370102

SCHEMBL5370102

CC(=O)c1cc(C)cc(C(C)=O)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.46
CYP2A6 P11509 1/20 0.39
TPMT P51580 1/20 0.39
ALDH1A1 P00352 4/20 0.38
ALOX15 P16050 2/20 0.37
TSHR P16473 2/20 0.37
HIF1A Q16665 1/20 0.37
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
KDM4E B2RXH2 2/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
NOS2 P35228 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ACMSD Q8TDX5 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HCAR1 Q9BXC0 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CA5A P35218 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17481789 0.89 SMN1; SMN2 (0.39) SMN1; SMN2CYP2A6TPMTALDH1A1ALOX15
SCHEMBL875421 0.88 NOS3 (0.43) SMN1; SMN2ALDH1A1LMNAKDM4EHPGD
SCHEMBL20223143 0.85 SMN1; SMN2 (0.44) SMN1; SMN2ALDH1A1LMNACYP1A2KDM4E
SCHEMBL30755869 0.84 SMN1; SMN2 (0.39) SMN1; SMN2CYP2A6TPMTALDH1A1LMNA
SCHEMBL13125496 0.84 SMN1; SMN2 (0.39) SMN1; SMN2CYP2A6TPMTALDH1A1KDM4E
SCHEMBL17440744 0.84 SMN1; SMN2 (0.39) SMN1; SMN2CYP2A6TPMTALDH1A1LMNA
SCHEMBL31494612 0.84 SMN1; SMN2 (0.39) SMN1; SMN2CYP2A6TPMTALDH1A1KDM4E
SCHEMBL18298077 0.81 SMN1; SMN2 (0.42) SMN1; SMN2ALDH1A1ALOX15TSHRHIF1A
SCHEMBL26162798 0.81 S1PR2 (0.40) SMN1; SMN2CYP2A6TPMTALDH1A1HTT
SCHEMBL26162800 0.80 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1KDM4ENOS2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823106-A Enhanced nucleic acid polymerization by aromatic compounds 豪夫迈·罗氏有限公司 2025-04-15 CN disclosed
CN-114144520-B Enhanced nucleic acid polymerization by aromatic compounds 豪夫迈·罗氏有限公司 2024-12-13 CN disclosed
CN-111771001-B Enhanced nucleic acid polymerization by aromatic compounds F·霍夫曼-罗氏股份公司 2024-09-06 CN disclosed
CN-111771001-A Enhanced nucleic acid polymerization by aromatic compounds 斯特拉托斯基因公司 2020-10-13 CN disclosed
US-20160031910-A1 LANTHANIDE COMPLEXES COMPRISING AT LEAST TWO BETAINE GROUPS, WHICH CAN BE USED AS LUMINESCENT MARKERS ECOLE NORMALE SUPERIEURE DE LYON (FR) 2016-02-04 US disclosed
CN-100519596-C Hollow polyethylene particles TOTAL PETROCHEMICALS RES FELUY (BE) 2009-07-29 CN disclosed
US-7300901-B2 Hollow beads of polyethylene TOTAL PETROCHEMICALS RESEARCH FELUY (BG) 2007-11-27 US disclosed
US-7300901-B2 Hollow beads of polyethylene TOTAL PETROCHEMICALS RESEARCH FELUY (BG) 2007-11-27 US disclosed
US-7300901-B2 Hollow beads of polyethylene TOTAL PETROCHEMICALS RESEARCH FELUY (BG) 2007-11-27 US disclosed
US-20070054799-A1 Hollow beads of polyethylene LAVASTRE OLIVIER 2007-03-08 US disclosed
US-20070054799-A1 Hollow beads of polyethylene LAVASTRE OLIVIER 2007-03-08 US disclosed
US-20070054799-A1 Hollow beads of polyethylene LAVASTRE OLIVIER 2007-03-08 US disclosed
US-20070032629-A1 Grafting of transition metal complexes on supports BANET PHILLIPE 2007-02-08 US disclosed
EP-1718684-A1 GRAFTING OF TRANSITION METAL COMPLEXES ON SUPPORTS. TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2006-11-08 EP disclosed
CN-1774454-A Hollow beads of polyethylene TOTAL PETROCHEMICALS RES FELUY (BE) 2006-05-17 CN disclosed
EP-1613673-A1 HOLLOW BEADS OF POLYETHYLENE TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2006-01-11 EP disclosed
WO-2005075522-A1 GRAFTING OF TRANSITION METAL COMPLEXES ON SUPPORTS. TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2005-08-18 WO disclosed
EP-1559728-A1 Grafting of transition metal complexes on supports TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2005-08-03 EP disclosed
WO-2004090000-A1 HOLLOW BEADS OF POLYETHYLENE TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2004-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160031910-A1 LANTHANIDE COMPLEXES COMPRISING AT LEAST TWO BETAINE GROUPS, WHICH CAN BE USED AS LUMINESCENT MARKERS SLC6A12, LGALS3, LBR SMN1; SMN2 4399/4885CYP2A6 4479/4885TPMT 3638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.