Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 8/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481957 | 0.79 | CHRM4 (0.45) | RIPK1CES2CES1CHRM4ROCK2 | |
| SCHEMBL584220 | 0.77 | FFAR1 (0.47) | RIPK1CES2CES1 | |
| SCHEMBL869863 | 0.76 | RIPK1 (0.47) | RIPK1CES2CES1 | |
| SCHEMBL29459925 | 0.76 | RIPK1 (0.47) | RIPK1CES2CES1 | |
| SCHEMBL4574283 | 0.75 | USP28 (0.40) | RIPK1CES2CES1 | |
| SCHEMBL29912778 | 0.75 | USP28 (0.40) | RIPK1CES2CES1 | |
| SCHEMBL29912873 | 0.74 | RIPK1 (0.40) | RIPK1CES2CES1CHRM4ROCK2 | |
| SCHEMBL12640806 | 0.74 | RIPK1 (0.40) | RIPK1CES2CES1CHRM4ROCK2 | |
| SCHEMBL29860418 | 0.74 | HTT (0.40) | RIPK1CES2CES1 | |
| SCHEMBL29788838 | 0.74 | RIPK1 (0.46) | RIPK1CES2CES1CHRM4ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134035-A1 | ALPHA-UNSUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-A] PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |