Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.44 |
| ▸ | TLR2 | O60603 | 3/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356099 | 1.00 | SLC6A5 (0.52) | SLC6A5FOLH1NOD1SIRT1TLR2 | |
| SCHEMBL457463 | 1.00 | SLC6A5 (0.52) | SLC6A5FOLH1NOD1SIRT1TLR2 | |
| SCHEMBL6688677 | 0.95 | NOD1 (0.47) | SLC6A5FOLH1NOD1ITGB3ITGA2B | |
| SCHEMBL6688681 | 0.95 | NOD1 (0.47) | SLC6A5FOLH1NOD1ITGB3ITGA2B | |
| SCHEMBL9716662 | 0.95 | NOD1 (0.47) | SLC6A5FOLH1NOD1ITGB3ITGA2B | |
| SCHEMBL30915502 | 0.94 | SLC6A5 (0.56) | SLC6A5FOLH1NOD1SIRT1TLR2 | |
| SCHEMBL7804980 | 0.94 | SLC6A5 (0.56) | SLC6A5FOLH1NOD1SIRT1TLR2 | |
| SCHEMBL7797291 | 0.94 | SLC6A5 (0.56) | SLC6A5FOLH1NOD1SIRT1TLR2 | |
| SCHEMBL7803299 | 0.94 | SLC6A5 (0.56) | SLC6A5FOLH1NOD1SIRT1TLR2 | |
| SCHEMBL7804955 | 0.94 | SLC6A5 (0.56) | SLC6A5FOLH1NOD1SIRT1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028814-A2 | NMDA RECEPTOR CHANNEL BLOCKER WITH NEUROPROTECTIVE ACTIVITY | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-04-11 | — | — | WO | disclosed |