Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27959617 | 0.69 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL10435582 | 0.63 | ALDH1A1 (0.38) | ALDH1A1HIF1A | |
| SCHEMBL6701234 | 0.62 | CYP2D6 (0.45) | CYP2D6ALDH1A1CYP2C19HIF1A | |
| SCHEMBL2223767 | 0.62 | — | — | |
| SCHEMBL8725908 | 0.62 | CYP2D6 (0.45) | CYP2D6ALDH1A1CYP2C19HIF1A | |
| SCHEMBL11591784 | 0.60 | CYP2D6 (0.38) | CYP2D6ALDH1A1CYP2C19HIF1A | |
| SCHEMBL4031715 | 0.58 | FFAR3 (0.39) | CYP2D6ALDH1A1CYP2C19HIF1A | |
| SCHEMBL13130591 | 0.58 | HSD17B10 (0.38) | CYP2D6ALDH1A1CYP2C19HIF1A | |
| Glycolic Acid SCHEMBL9013528 | 0.58 | ALDH1A1 (0.37) | CYP2D6ALDH1A1CYP2C19HIF1A | |
| SCHEMBL13129910 | 0.58 | CYP2D6 (0.42) | CYP2D6ALDH1A1CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194524-A1 | Compounds For the Inhibition of Undesired Cell Proliferation and Use Thereof | JERINI AG (DE) | 2008-08-14 | — | — | US | disclosed |
| EP-1703912-A1 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | Jerini AG (DE) | 2006-09-27 | — | — | EP | disclosed |
| WO-2005063259-A1 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194524-A1 | Compounds For the Inhibition of Undesired Cell Proliferation and Use Thereof | CCNB1, CCNB2, CCNA1 | CYP2D6 1594/4885ALDH1A1 1521/4885CYP2C19 757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.