Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMAD3 | P84022 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | THRB | P10828 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | BLM | P54132 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GLB1 | P16278 | 1/20 | 0.58 |
| ▸ | CTRC | Q99895 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1463748 | 0.90 | SMAD3 (0.65) | SMAD3RECQLTDP1THRBMEN1 | |
| SCHEMBL1444969 | 0.89 | SMAD3 (0.77) | SMAD3RECQLTDP1THRBMEN1 | |
| SCHEMBL30887311 | 0.86 | ALDH1A1 (0.63) | SMAD3RECQLTDP1THRBMEN1 | |
| SCHEMBL30887310 | 0.86 | ALDH1A1 (0.63) | SMAD3RECQLTDP1THRBMEN1 | |
| SCHEMBL134733 | 0.86 | ALDH1A1 (0.63) | SMAD3RECQLTDP1THRBMEN1 | |
| SCHEMBL29361906 | 0.86 | ALDH1A1 (0.63) | SMAD3RECQLTDP1THRBMEN1 | |
| SCHEMBL5453230 | 0.85 | ALDH1A1 (0.62) | SMAD3RECQLTDP1THRBMEN1 | |
| SCHEMBL23860297 | 0.84 | RECQL (0.57) | SMAD3RECQLTDP1THRBMEN1 | |
| SCHEMBL1444919 | 0.83 | THRB (0.85) | SMAD3RECQLTDP1THRBMEN1 | |
| SCHEMBL5711381 | 0.83 | FTO (0.50) | SMAD3RECQLTDP1THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008003954-A1 | DYE IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2008-01-10 | — | — | WO | disclosed |