Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GLP1R | P43220 | 3/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212437 | 0.85 | MEN1 (0.63) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8222261 | 0.81 | LMNA (0.43) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4748736 | 0.78 | DRD2 (0.43) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4574603 | 0.77 | KMT2A (0.53) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8214020 | 0.76 | KMT2A (0.54) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8220164 | 0.76 | MEN1 (0.54) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8224487 | 0.76 | KMT2A (0.54) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8220055 | 0.75 | KMT2A (0.59) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4575198 | 0.75 | LMNA (0.46) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4575368 | 0.73 | KMT2A (0.47) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | claimed |
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | disclosed |