Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GLP1R | P43220 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748294 | 0.87 | KMT2A (0.49) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4847919 | 0.87 | KMT2A (0.49) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4574785 | 0.85 | MEN1 (0.57) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4847934 | 0.84 | KMT2A (0.45) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8223212 | 0.83 | MEN1 (0.51) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8220164 | 0.82 | MEN1 (0.54) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8221394 | 0.80 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8213895 | 0.79 | MEN1 (0.49) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4747652 | 0.79 | KMT2A (0.52) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4744996 | 0.78 | DRD2 (0.46) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | disclosed |