Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.89 |
| ▸ | CA4 | P22748 | 2/20 | 0.89 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 11/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL11789341 | 0.97 | CA2 (0.94) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL1445056 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL579255 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL4525348 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL12476955 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL944537 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL1798863 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL20570232 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL20570059 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL188041 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 584 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220289959-A1 | ELASTOMER COMPOSITION FOR ACTUATOR, ACTUATOR MEMBER, AND ACTUATOR ELEMENT | ENEOS CORPORATION (JP) | 2022-09-15 | — | — | US | claimed |
| US-20220282036-A1 | A PROCESS FOR MANUFACTURING SPECIALTY POLYESTERS & CO-POLYESTERS FROM RECYCLED BIS 2-HYDROXYETHYL TEREPHTHALATE (rBHET) AND PRODUCT THEREOF | KULKARNI SANJAY TAMMAJI (IN) | 2022-09-08 | — | — | US | claimed |
| EP-4023706-A1 | ELASTOMER COMPOSITION FOR ACTUATOR, ACTUATOR MEMBER, AND ACTUATOR ELEMENT | ENEOS Corporation (JP) | 2022-07-06 | — | — | EP | claimed |
| CN-114599713-A | Process for making specialty polyesters and copolyesters from recycled bis-2-hydroxyethyl terephthalate (rBHET) and products thereof | 桑贾伊·塔玛吉·库尔卡尼 | 2022-06-07 | — | — | CN | claimed |
| CN-114258416-A | Elastomer composition for actuator, actuator component and actuator element | 引能仕株式会社 | 2022-03-29 | — | — | CN | claimed |
| EP-3448924-B1 | CONTROLLED POLYMER FOAMING USING A HYBRID NUCLEATING AGENT FORMED FROM A MINERAL AND AN ORGANIC NUCLEATING AGENT | IMERYS TALC AMERICA INC (US) | 2021-08-18 | — | — | EP | claimed |
| WO-2021038512-A1 | A PROCESS FOR MANUFACTURING SPECIALTY POLYESTERS & CO-POLYESTERS FROM RECYCLED BIS 2-HYDROXYETHYL TEREPHTHALATE (RBHET) AND PRODUCT THEREOF | KULKARNI SANJAY TAMMAJI (IN) | 2021-03-04 | — | — | WO | claimed |
| WO-2021039821-A1 | ELASTOMER COMPOSITION FOR ACTUATOR, ACTUATOR MEMBER, AND ACTUATOR ELEMENT | ＥＮＥＯＳ株式会社 | 2021-03-04 | — | — | WO | claimed |
| US-10479889-B2 | Thermoplastic resin composition, molded article made therefrom, and method of preparing the composition | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2019-11-19 | — | — | US | claimed |
| US-20170335054-A1 | HEAT RESISTANT POLYETHYLENE TEREPHTHALATE AND PROCESS OF MANUFACTURING THEREOF | ESTER INDUSTRIES LIMITED (IN) | 2017-11-23 | — | — | US | claimed |
| EP-3221400-A2 | HEAT RESISTANT POLYETHYLENE TEREPHTHALATE AND PROCESS OF MANUFACTURING THEREOF | Ester Industries Limited (IN) | 2017-09-27 | — | — | EP | claimed |
| US-20160185954-A1 | THERMOPLASTIC RESIN COMPOSITION, MOLDED ARTICLE MADE THEREFROM, AND METHOD OF PREPARING THE COMPOSITION | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-06-30 | — | — | US | claimed |
| US-20160168321-A1 | HEAT RESISTANT POLYETHYLENE TEREPHTHALATE AND A PROCESS FOR THE PREPARATION OF THE SAME | ESTER INDUSTRIES LIMITED (IN) | 2016-06-16 | — | — | US | claimed |
| EP-2999733-A1 | HEAT RESISTANT POLYETHYLENE TEREPHTHALATE AND A PROCESS FOR THE PREPARATION OF THE SAME | Ester Industries Limited (IN) | 2016-03-30 | — | — | EP | claimed |
| EP-1135251-A4 | OPAQUE POLYMERIC FILMS AND PROCESSES FOR MAKING THE SAME | EXXONMOBIL OIL CORP (US) | 2003-04-16 | — | — | EP | claimed |
| US-6303233-B1 | DIMENTIONAL STABILITY; PACKAGES, WRAPPING | MOBIL OIL CORPORATION | 2001-10-16 | — | — | US | claimed |
| EP-1135251-A1 | OPAQUE POLYMERIC FILMS AND PROCESSES FOR MAKING THE SAME | MOBIL OIL CORPORATION (US) | 2001-09-26 | — | — | EP | claimed |
| US-6194060-B1 | Opaque polymeric films and processes for making the same | MOBIL OIL CORPORATION | 2001-02-27 | — | — | US | claimed |
| WO-2000048829-A1 | OPAQUE POLYMERIC FILMS AND PROCESSES FOR MAKING THE SAME | MOBIL OIL CORPORATION (US) | 2000-08-24 | — | — | WO | claimed |
| WO-1999051432-A1 | UNIAXIALLY SHRINKABLE BIAXIALLY ORIENTED POLYPROPYLENE FILM | MOBIL OIL CORPORATION (US) | 1999-10-14 | — | — | WO | claimed |