Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.89 |
| ▸ | CA4 | P22748 | 2/20 | 0.89 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 11/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL11789341 | 0.97 | CA2 (0.94) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL944537 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL394354 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL12476955 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL1445056 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL1798863 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL4525348 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL20570232 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL20570059 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL457494 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210222118-A1 | CHARCOAL-FREE CULTURE MEDIA FOR LEGIONELLA | Secretary of State for Health and Social Care (GB) | 2021-07-22 | — | — | US | claimed |
| EP-3841214-A1 | CHARCOAL-FREE CULTURE MEDIA FOR LEGIONELLA | Secretary of State for Health and Social Care (GB) | 2021-06-30 | — | — | EP | claimed |
| CN-112888790-A | Legionella carbon-free culture medium | 英国卫生与社会保障部 | 2021-06-01 | — | — | CN | claimed |
| WO-2020039213-A1 | CHARCOAL-FREE CULTURE MEDIA FOR LEGIONELLA | Secretary of State for Health and Social Care (GB) | 2020-02-27 | — | — | WO | claimed |
| US-8642679-B2 | Dental cement composition | GC CORPORATION (JP) | 2014-02-04 | — | — | US | claimed |
| EP-2416756-A2 | STABLE PHARMACEUTICAL COMPOSITIONS WITH HIGH BIOAVAILIBILITY | Bilgic, Mahmut (TR) | 2012-02-15 | — | — | EP | claimed |
| WO-2010117346-A2 | STABLE PHARMACEUTICAL COMPOSITIONS WITH HIGH BIOAVAILIBILITY | BILGIC MAHMUT (TR) | 2010-10-14 | — | — | WO | claimed |
| US-20100068678-A1 | CEMENT FOR SEALER | GC CORPORATION (JP) | 2010-03-18 | — | — | US | claimed |
| EP-2163232-A1 | Cement for sealer | GC Corporation (JP) | 2010-03-17 | — | — | EP | claimed |
| US-5789471-A | Polyvinyl chloride composition having enhanced light transmission and reflection characteristics | SUPER VISION INTERNATIONAL, INC. (US) | 1998-08-04 | — | — | US | claimed |
| EP-0416321-B1 | Crystalline polyolefin composition | CHISSO CORP (JP) | 1994-11-09 | — | — | EP | claimed |
| US-5063264-A | Molding materials | CHISSO CORPORATION (JP) | 1991-11-05 | — | — | US | claimed |
| EP-0416321-A1 | Crystalline polyolefin composition | Chisso Corporation (JP) | 1991-03-13 | — | — | EP | claimed |
| US-20260116916-A1 | METHODS FOR ENHANCED REMOVAL OF IMPURITIES DURING PROTEIN A CHROMATOGRAPHY | GENZYME CORP (US) | 2026-04-30 | — | — | US | disclosed |
| US-12528835-B2 | Methods for enhanced removal of impurities during protein a chromatography | GENZYME CORPORATION (US) | 2026-01-20 | — | — | US | disclosed |
| US-20250243077-A1 | METHODS AND SYSTEMS FOR STRONTIUM IMPURITY EXTRACTION | ZENO POWER SYSTEMS, INC. (US) | 2025-07-31 | — | — | US | disclosed |
| US-4151099-A | POLYETHOXYLATED ESTER, SULFURIZED MOLYBDENUM OR ANTIMONY ORGANOPHOSPHORODITHIOATE | BASF WYANDOTTE CORPORATION (US) | 1979-04-24 | — | — | US | disclosed |
| US-3985797-A | Hydroxylation of aromatic compounds | UOP INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3985796-A | Hydroxylation of aromatic compounds | UOP INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3931295-A | Hydroxylation of aromatic compounds | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12528835-B2 | Methods for enhanced removal of impurities during protein a chromatography | F13A1, SSB, FCGR2A | CA2 20/4885CA4 145/4885CES1 2066/4885 |
| US-20260116916-A1 | METHODS FOR ENHANCED REMOVAL OF IMPURITIES DURING PROTEIN A CHROMATOGRAPHY | MAX, F13A1, F11 | CA2 90/4885CA4 212/4885CES1 2249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.