Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | MC5R | P33032 | 4/20 | 0.51 |
| ▸ | MC4R | P32245 | 2/20 | 0.51 |
| ▸ | MC3R | P41968 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | MC1R | Q01726 | 2/20 | 0.47 |
| ▸ | FCER2 | P06734 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29833616 | 1.00 | HTR2A (0.59) | HTR2AHTR2CHTR2BDPP4EPHX1 | |
| SCHEMBL16064400 | 1.00 | HTR2A (0.59) | HTR2AHTR2CHTR2BDPP4EPHX1 | |
| Hydrochloric Acid SCHEMBL8740504 | 0.98 | HTR2A (0.57) | HTR2AHTR2CHTR2BDPP4EPHX1 | |
| Trifluoroacetic Acid SCHEMBL31734190 | 0.90 | HTR2A (0.49) | HTR2AHTR2CHTR2BDPP4EPHX1 | |
| SCHEMBL837890 | 0.86 | SLC7A5 (0.65) | HTR2AHTR2CHTR2BDPP4MC5R | |
| SCHEMBL15745967 | 0.86 | HTR2A (0.64) | HTR2AHTR2CHTR2BDPP4MC5R | |
| SCHEMBL93304 | 0.86 | SLC7A5 (0.65) | HTR2AHTR2CHTR2BDPP4MC5R | |
| SCHEMBL17874879 | 0.86 | HTR2A (0.64) | HTR2AHTR2CHTR2BDPP4MC5R | |
| SCHEMBL93303 | 0.86 | SLC7A5 (0.65) | HTR2AHTR2CHTR2BDPP4MC5R | |
| SCHEMBL10069405 | 0.86 | HTR2A (0.64) | HTR2AHTR2CHTR2BDPP4MC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180312463-A1 | Synthesis of Cyclohexane Carboxamide Derivatives Useful as Sensates in Consumer Products | PROCTER & GAMBLE (US) | 2018-11-01 | — | — | US | disclosed |
| US-20170057911-A1 | SYNTHESIS OF ARYL CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | PROCTER & GAMBLE (US) | 2017-03-02 | — | — | US | disclosed |
| US-7446115-B2 | To treat pain, drug addiction, or tinnitus; selectively inhibit sodium or calcium ion channels and agonize or antagonize mu -opioid receptors; N-Benzyl-N-(2-dimethylamino-ethyl)-2-(S)-[3-(4-fluorophenyl)-ureido]-3-methyl-butyramide | SEPRACOR, INC. (US) | 2008-11-04 | — | — | US | disclosed |
| US-20080194524-A1 | Compounds For the Inhibition of Undesired Cell Proliferation and Use Thereof | JERINI AG (DE) | 2008-08-14 | — | — | US | disclosed |
| EP-1490044-A4 | COMBINATION THERAPY FOR THE TREATMENT OF CONDITIONS WITH PATHOGENIC INFLAMMATORY COMPONENTS | NEUROGEN CORP (US) | 2008-04-16 | — | — | EP | disclosed |
| US-20070093522-A1 | Peptidomimetic ligands for cellular receptors and ion channels | PERSONS PAUL E | 2007-04-26 | — | — | US | disclosed |
| EP-1703912-A1 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | Jerini AG (DE) | 2006-09-27 | — | — | EP | disclosed |
| WO-2005063259-A1 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-07-14 | — | — | WO | disclosed |
| EP-1490044-A1 | COMBINATION THERAPY FOR THE TREATMENT OF CONDITIONS WITH PATHOGENIC INFLAMMATORY COMPONENTS | NEUROGEN CORPORATION (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003084524-A1 | COMBINATION THERAPY FOR THE TREATMENT OF CONDITIONS WITH PATHOGENIC INFLAMMATORY COMPONENTS | NEUROGEN CORPORATION (US) | 2003-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093522-A1 | Peptidomimetic ligands for cellular receptors and ion channels | OPRL1, TRPV1, ORAI1 | HTR2A 274/4885HTR2C 318/4885HTR2B 463/4885 |
| US-20180312463-A1 | Synthesis of Cyclohexane Carboxamide Derivatives Useful as Sensates in Consumer Products | SRM, ACMSD, CUTA | HTR2A 49/4885HTR2C 108/4885HTR2B 89/4885 |
| US-20080194524-A1 | Compounds For the Inhibition of Undesired Cell Proliferation and Use Thereof | CCNB1, CCNB2, CCNA1 | HTR2A 4056/4885HTR2C 4167/4885HTR2B 3009/4885 |
| US-20170057911-A1 | SYNTHESIS OF ARYL CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | CUTA, ACMSD, SRM | HTR2A 50/4885HTR2C 99/4885HTR2B 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.