Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.59 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729335 | 0.84 | GPR84 (0.59) | SLC6A5CA2EPHX2LTA4HL3MBTL1 | |
| SCHEMBL6638762 | 0.81 | ADRB3 (0.59) | EPHX2LTA4HADRB3MEN1KMT2A | |
| SCHEMBL8348550 | 0.80 | SCN8A (0.55) | BCHESCN8AEPHX2MEN1KMT2A | |
| SCHEMBL4575081 | 0.80 | MTOR (0.56) | BCHESLC6A5CA1CA2SCN8A | |
| Hydrochloric Acid SCHEMBL6122751 | 0.78 | SCN8A (0.54) | BCHESCN8AEPHX2NR1H4 | |
| Hydrochloric Acid SCHEMBL7724235 | 0.78 | EPHX2 (0.48) | SLC6A5SCN8AEPHX2LTA4HGPR84 | |
| Hydrochloric Acid SCHEMBL5313712 | 0.78 | SLC6A5 (0.55) | BCHESLC6A5CA1CA2SCN8A | |
| SCHEMBL4656040 | 0.78 | SCN8A (0.59) | SLC6A5SCN8AEPHX2MEN1KMT2A | |
| SCHEMBL9903315 | 0.78 | SCN8A (0.58) | SLC6A5CA1CA2SCN8AEPHX2 | |
| SCHEMBL19243611 | 0.78 | SCN8A (0.55) | BCHESCN8AEPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319104-B2 | hPPARs activators | SMITHKLINE BEECHAM CORPORATION (US) | 2008-01-15 | — | — | US | disclosed |
| EP-1480957-A1 | HPPARS ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074495-A1 | HPPARS ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-12 | — | — | WO | disclosed |