Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938063 | 0.88 | ESR1 (0.56) | GPR84ESR1ESR2NLRP3EPHX2 | |
| SCHEMBL221511 | 0.87 | MAPT (0.52) | GPR84ESR1ESR2EPHX2ALDH1A1 | |
| SCHEMBL12952731 | 0.85 | APP (0.59) | SLC6A2CYP2C19SLC6A3MAPT | |
| SCHEMBL4575327 | 0.84 | BCHE (0.59) | GPR84LTA4HSLC6A5CA2EPHX2 | |
| SCHEMBL700042 | 0.82 | PPARA (0.56) | GPR84DAOLTA4HCA2EPHX2 | |
| SCHEMBL9062148 | 0.82 | TSHR (0.53) | GPR84DAOLTA4HEPHX2ALDH1A1 | |
| SCHEMBL4307301 | 0.81 | MEN1 (0.64) | ESR1ESR2LTA4HEPHX2KDM4E | |
| SCHEMBL508237 | 0.81 | AURKA (0.57) | ESR1ESR2EPHX2MAPT | |
| SCHEMBL9589201 | 0.81 | MEN1 (0.64) | ESR1ESR2LTA4HEPHX2KDM4E | |
| SCHEMBL3414927 | 0.80 | ESR1 (0.56) | ESR1ESR2CALM1LTA4HCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| US-5858270-A | Difluorooxymethane derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |