Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.62 |
| ▸ | ABAT | P80404 | 1/20 | 0.62 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.57 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288138 | 0.86 | ALDH5A1 (0.57) | ALDH5A1ABATVCAM1ALDH3A1ALDH1A1 | |
| SCHEMBL2924523 | 0.84 | ALDH3A1 (0.62) | ALDH5A1ABATVCAM1ALDH3A1ALDH1A1 | |
| SCHEMBL14548858 | 0.83 | ALDH5A1 (0.57) | ALDH5A1ABATVCAM1ALDH3A1ALDH1A1 | |
| SCHEMBL6355056 | 0.83 | ALDH5A1 (0.57) | ALDH5A1ABATVCAM1ALDH3A1ALDH1A1 | |
| SCHEMBL8759780 | 0.83 | ALDH5A1 (0.57) | ALDH5A1ABATVCAM1ALDH3A1ALDH1A1 | |
| SCHEMBL6355401 | 0.82 | CYP1A2 (0.65) | ALDH5A1ABATVCAM1ALDH3A1ALDH1A1 | |
| SCHEMBL27780985 | 0.81 | ALDH5A1 (0.56) | ALDH5A1ABATVCAM1ALDH3A1ALDH1A1 | |
| SCHEMBL5981396 | 0.81 | ALDH5A1 (0.55) | ALDH5A1ABATVCAM1ALDH3A1ALDH1A1 | |
| SCHEMBL31442858 | 0.81 | ALDH5A1 (0.55) | ALDH5A1ABATVCAM1ALDH3A1ALDH1A1 | |
| SCHEMBL6045765 | 0.80 | ALDH5A1 (0.54) | ALDH5A1ABATVCAM1ALDH3A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132484-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | ACatechol, Inc. (US) | 2017-08-03 | — | — | WO | disclosed |
| US-20170217997-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | ORMCO CORPORATION | 2017-08-03 | — | — | US | disclosed |
| US-20080221303-A1 | Method for the Preparation of Peptide-Oligonucleotide Conjugates | FRUTAROM LTD. (IL) | 2008-09-11 | — | — | US | disclosed |
| EP-1725250-A2 | METHOD FOR THE PREPARATION OF PEPTIDE-OLIGONUCLEOTIDE CONJUGATES | FRUTAROM LTD. (IL) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005076744-A2 | METHOD FOR THE PREPARATION OF PEPTIDE-OLIGONUCLEOTIDE CONJUGATES | FRUTAROM LTD. (IL) | 2005-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217997-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, ESR1 | ALDH5A1 2751/4885ABAT 4582/4885VCAM1 1633/4885 |
| US-20080221303-A1 | Method for the Preparation of Peptide-Oligonucleotide Conjugates | VIP, PTMS, SSTR4 | ALDH5A1 4427/4885ABAT 3436/4885VCAM1 1128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.