SCHEMBL4575613

SCHEMBL4575613

CC(C)Cc1ccc(Oc2ccc(CC(C)C)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.48
PTGS2 P35354 4/20 0.45
PTGS1 P23219 3/20 0.45
LMNA P02545 2/20 0.45
CYP2C9 P11712 2/20 0.45
AKR1C3 P42330 2/20 0.45
CXCR1 P25024 2/20 0.45
CXCR2 P25025 2/20 0.45
ALB P02768 1/20 0.45
ESR1 P03372 1/20 0.45
ALOX5 P09917 1/20 0.45
RARB P10826 1/20 0.45
ADRB3 P13945 1/20 0.45
NFKB1 P19838 1/20 0.45
HTR2A P28223 1/20 0.45
NR1I3 Q14994 1/20 0.45
SLC22A6 Q4U2R8 1/20 0.45
CXCL8 P10145 1/20 0.45
TSHR P16473 1/20 0.45
AKR1C2 P52895 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL10608866 0.91 PTGS2 (0.50) SLC6A4PTGS2PTGS1LMNACYP2C9
SCHEMBL13719143 0.91 SLC6A4 (0.62) SLC6A4
SCHEMBL9252743 0.91 LTA4H (0.55) TSHR
SCHEMBL13719538 0.91 TEAD4 (0.48) SLC6A4PTGS2PTGS1LMNACYP2C9
SCHEMBL25146419 0.89 ESR1 (0.56) ESR1ADRB3
SCHEMBL8056212 0.89 TRPA1 (0.48) SLC6A4
SCHEMBL13719535 0.89 SLC6A2 (0.53) SLC6A4
SCHEMBL13719134 0.89 MAPT (0.47) SLC6A4PTGS2PTGS1LMNACYP2C9
SCHEMBL18686311 0.86 ESR1 (0.44) SLC6A4PTGS2PTGS1LMNACYP2C9
SCHEMBL21446844 0.86 SLC2A1 (0.51)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080244963-A1 Lead-Free Aviation Fuel TOTAL FRANCE (FR) 2008-10-09 US claimed
EP-0127681-B1 IGA BINDING PROTEIN THE ROCKEFELLER UNIVERSITY (US) 1993-03-03 EP claimed
CN-114315783-A Chromogenic peroxidase substrates 安捷伦科技有限公司 2022-04-12 CN disclosed
US-20080244963-A1 Lead-Free Aviation Fuel TOTAL FRANCE (FR) 2008-10-09 US disclosed