Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7557564 | 0.81 | GRIN2D (0.34) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4575448 | 0.81 | ALDH1A1 (0.35) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL28117836 | 0.74 | TSHR (0.39) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL7832148 | 0.70 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1MAPTPOLB | |
| SCHEMBL18884997 | 0.69 | — | — | |
| SCHEMBL11503297 | 0.67 | KMT2A (0.40) | ALDH1A1TSHRTDP1MAPTPOLB | |
| SCHEMBL27336012 | 0.65 | ALOX15 (0.43) | ALDH1A1TSHRGPR35MAPTSMN1; SMN2 | |
| SCHEMBL4575373 | 0.64 | MAPT (0.37) | ALDH1A1MAPTPOLBSMN1; SMN2KDM4E | |
| SCHEMBL4235814 | 0.64 | ALDH1A1 (0.37) | ALDH1A1TSHRMAPTPOLB | |
| Alcohol SCHEMBL10696050 | 0.63 | ALDH1A1 (0.39) | ALDH1A1TSHRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008039087-A2 | INDOLINE DERIVATIVES AND USES THEREOF | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-04-03 | — | — | WO | disclosed |
| EP-0850224-A1 | RADIATION-ACTIVATED CYTOTOXIN THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997007101-A1 | RADIATION-ACTIVATED CYTOTOXIN THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 1997-02-27 | — | — | WO | disclosed |