Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8402490 | 0.86 | NFKB1 (0.56) | NFKB1CA1CA2CA4SMN1; SMN2 | |
| SCHEMBL818741 | 0.86 | NFKB1 (0.56) | NFKB1CA1CA2CA4SMN1; SMN2 | |
| SCHEMBL13505415 | 0.80 | NFKB1 (0.50) | NFKB1CA1CA2CA4SMN1; SMN2 | |
| Tert-Butylamine SCHEMBL1879653 | 0.79 | CA1 (0.53) | NFKB1CA1CA2CA4SMN1; SMN2 | |
| Tert-Butylamine SCHEMBL1879651 | 0.79 | CA1 (0.53) | NFKB1CA1CA2CA4SMN1; SMN2 | |
| SCHEMBL82266 | 0.79 | NFKB1 (0.77) | NFKB1CA1CA2CA4SMN1; SMN2 | |
| SCHEMBL8055837 | 0.79 | NFKB1 (0.77) | NFKB1CA1CA2CA4SMN1; SMN2 | |
| SCHEMBL29365331 | 0.79 | NFKB1 (0.77) | NFKB1CA1CA2CA4SMN1; SMN2 | |
| SCHEMBL82267 | 0.79 | NFKB1 (0.77) | NFKB1CA1CA2CA4SMN1; SMN2 | |
| Cinnamic Acid SCHEMBL11762312 | 0.78 | HCAR2 (0.58) | CA1CA2CA4SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008039087-A2 | INDOLINE DERIVATIVES AND USES THEREOF | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-04-03 | — | — | WO | disclosed |