SCHEMBL818741

SCHEMBL818741

CC(C)(C)c1ccccc1/C=C/C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA4 P22748 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.49
HTT P42858 1/20 0.49
MAPT P10636 1/20 0.49
HDAC3 O15379 1/20 0.48
TNKS O95271 1/20 0.48
HDAC4 P56524 1/20 0.48
HDAC1 Q13547 1/20 0.48
HCAR2 Q8TDS4 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
TNKS2 Q9H2K2 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
HDAC9 Q9UKV0 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8402490 1.00 NFKB1 (0.56) NFKB1CA1CA2CA4SMN1; SMN2
SCHEMBL28868256 0.88 NFKB1 (0.44) NFKB1CA1CA2CA4SMN1; SMN2
SCHEMBL22026727 0.87 NFKB1 (0.68) NFKB1SMN1; SMN2MAPTMAOBMAPK1
SCHEMBL4575755 0.86 NFKB1 (0.53) NFKB1CA1CA2CA4SMN1; SMN2
SCHEMBL27724914 0.84 ALOX12 (0.54) NFKB1CA1CA2CA4HTT
SCHEMBL9788936 0.84 NFKB1 (0.50) NFKB1CA1CA2CA4MAPT
SCHEMBL8529144 0.84 NFKB1 (0.50) NFKB1MAPTMAOBKMT2AP4HB
SCHEMBL13505415 0.83 NFKB1 (0.50) NFKB1CA1CA2CA4SMN1; SMN2
SCHEMBL8055837 0.81 NFKB1 (0.77) NFKB1CA1CA2CA4SMN1; SMN2
SCHEMBL9789089 0.81 NFKB1 (0.43) NFKB1CA1CA2CA4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6884567-B2 Photosensitive formulation for buffer coatings, film containing the photosensitive formulation, and method for fabricating electronics with the photosensitive formulation INFINEON TECHNOLOGIES AG (DE) 2005-04-26 US claimed
US-20030099904-A1 Photosensitive formulation for buffer coatings, film containing the photosensitive formulation, and method for fabricating electronics with the photosensitive formulation POLARIS INNOVATIONS LIMITED (IE) 2003-05-29 US claimed
WO-2025057784-A1 ACTIVE LIGHT-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTIVE LIGHT-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE 富士フイルム株式会社 2025-03-20 WO disclosed
CN-109071446-B Organic reaction in aqueous solution in the presence of hydroxyalkyl (alkyl) cellulose or alkylcellulose 艾伯维德国有限责任两合公司 2022-06-21 CN disclosed
US-20110275745-A1 MODIFIED MAGNESIUM OXYSULFATE FIBROUS PARTICLES AND POLYOLEFIN COMPOSITION CONTAINING THE SAME UBE MATERIAL INDUSTRIES, LTD. (JP) 2011-11-10 US disclosed
US-20100121069-A1 METHOD FOR MANUFACTURING A BETA-DIARYL ELECTRON WITHDRAWING GROUP SUBSTITUTED COMPOUND MSD K.K. (JP) 2010-05-13 US disclosed
US-20090292047-A1 MODIFIED MAGNESIUM OXYSULFATE FIBROUS PARTICLES AND POLYOLEFIN COMPOSITION CONTAINING THE SAME UBE MATERIAL INDUSTRIES, LTD. (JP) 2009-11-26 US disclosed
EP-2042478-A1 METHOD FOR PRODUCING -DIARYL ELECTRON-WITHDRAWING GROUP SUBSTITUTED COMPOUND Japan Science and Technology Agency (JP) 2009-04-01 EP disclosed
US-20070203019-A1 Phase selective polymer supports for catalysis BERGBREITER DAVID E 2007-08-30 US disclosed
US-7211705-B2 Phase selective polymer supports for catalysis THE TEXAS A&M UNIVERSITY SYSTEM (US) 2007-05-01 US disclosed
US-7041667-B1 CCR5 modulators PFIZER, INC. (US) 2006-05-09 US disclosed
US-6479424-B1 FOR PRODUCING OLEFIN POLYMERS AND ESPECIALLY ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. 2002-11-12 US disclosed
EP-1157047-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP Corporation North America Inc. (US) 2001-11-28 EP disclosed
EP-0802920-B1 ANTIFUNGAL FUSACANDINS ABBOTT LAB (US) 2001-10-04 EP disclosed
EP-1013276-A1 Aminoazacycloalkanes as CCR5 modulators PFIZER INC. (US) 2000-06-28 EP disclosed
WO-2000035975-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. (US) 2000-06-22 WO disclosed
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed
EP-0253501-A2 N-disubstituted cycloalkylmethyl amines useful as fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-01-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100121069-A1 METHOD FOR MANUFACTURING A BETA-DIARYL ELECTRON WITHDRAWING GROUP SUBSTITUTED COMPOUND BMP6, GPR6, ACSL6 NFKB1 4076/4885CA1 3067/4885CA2 926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.