Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | STK39 | Q9UEW8 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30168074 | 0.70 | AKR1B1 (1.00) | AKR1B1TSHRHSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL4575982 | 0.70 | AKR1B1 (1.00) | AKR1B1TSHRHSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL68191 | 0.68 | HSD17B10 (0.77) | AKR1B1TSHRHSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL10706723 | 0.68 | TSHR (0.57) | TSHRALDH1A1CYP3A4KMT2AMAPT | |
| SCHEMBL29542318 | 0.68 | AKR1B1 (0.47) | AKR1B1STK39TSHRHSD17B10ALDH1A1 | |
| SCHEMBL435162 | 0.68 | AKR1B1 (0.68) | AKR1B1STK39TSHRHSD17B10ALDH1A1 | |
| SCHEMBL4586762 | 0.67 | TTR (0.63) | STK39TSHRHSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL11663615 | 0.67 | CA1 (0.43) | STK39TSHRALDH1A1HPGDTTR | |
| SCHEMBL272067 | 0.67 | HSD17B10 (0.55) | AKR1B1STK39TSHRHSD17B10ALDH1A1 | |
| SCHEMBL11222220 | 0.66 | HSP90AA1 (0.52) | STK39TSHRHSD17B10ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379058-B1 | Vinyl ester resins containing mesogenic/rigid rodlike moieties | DOW CHEMICAL CO (US) | 1999-09-29 | — | — | EP | claimed |
| EP-0379058-B1 | Vinyl ester resins containing mesogenic/rigid rodlike moieties | DOW CHEMICAL CO (US) | 1999-09-29 | — | — | EP | disclosed |
| US-5424393-A | Curing into liquid crystals | THE DOW CHEMICAL COMPANY (US) | 1995-06-13 | — | — | US | disclosed |
| US-5248740-A | Thioepoxides, liquid crystal polymers | THE DOW CHEMICAL COMPANY (US) | 1993-09-28 | — | — | US | disclosed |