Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.32 |
| ▸ | TUBB | P07437 | 2/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918844 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRPDE3BPDE3AMAPT | |
| SCHEMBL30626955 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRPDE3BPDE3AGAA | |
| SCHEMBL28569874 | 0.76 | TRPA1 (0.50) | TRPA1ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL13801049 | 0.76 | TRPA1 (0.53) | TRPA1ALDH1A1TSHRGAAMAPT | |
| SCHEMBL5613600 | 0.76 | CYP1A1 (0.55) | TRPA1ALDH1A1GAAMAPTCYP1A1 | |
| SCHEMBL28781669 | 0.76 | PDE3B (0.38) | PDE3BPDE3AGAAMAPTKDM4E | |
| SCHEMBL4576879 | 0.75 | CYP1A1 (0.65) | ALDH1A1TSHRGAAMAPTKMT2A | |
| SCHEMBL4576878 | 0.75 | CYP1A1 (0.65) | ALDH1A1TSHRGAAMAPTKMT2A | |
| SCHEMBL16959301 | 0.75 | TRPA1 (0.58) | TRPA1ALDH1A1TSHRGAACYP1A1 | |
| SCHEMBL727024 | 0.74 | TRPA1 (0.62) | TRPA1ALDH1A1GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2023-06-08 | — | — | US | disclosed |
| CN-104744243-B | (E)-2-phenyl-3-(3,5-dimethoxy-4 '-isopropyl benzene) purification method of propenoic acid | HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-104744243-A | Purifying method of (E)-2-phenyl-3-(3,5-dimethoxy-4-isopropyl benzene) crylic acid | UNIV HEBEI SCIENCE & TECH | 2015-07-01 | — | — | CN | disclosed |
| CN-1688535-B | Novel bioactive diphenyl ethene compounds and their therapeutic applications | BEIJING WENFENG TIANJI MEDICINE TECHNOLOGY CO LTD | 2011-11-09 | — | — | CN | disclosed |
| US-20080255245-A1 | Anti-Inflammatory and Psoriasis Treatment and Protein Kinase Inhibition by Hydroxystilbenes and Novel Stilbene Derivatives and Analogues | WELICHEM BIOTECH INC. (CA) | 2008-10-16 | — | — | US | disclosed |
| US-7321050-B2 | Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues | WELICHEM BIOTECH INC. (CA) | 2008-01-22 | — | — | US | disclosed |
| CN-1688535-A | Novel bioactive diphenyl ethene compounds and their therapeutic applications | WELICHEM BIOTECH INC (CA) | 2005-10-26 | — | — | CN | disclosed |
| US-20050059733-A1 | Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues | WELICHEM BIOTECH, INC. | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059733-A1 | Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues | NFKBIA, IKBKB, IKBKE | TRPA1 1750/4885ALDH1A1 3063/4885TSHR 3934/4885 |
| US-20080255245-A1 | Anti-Inflammatory and Psoriasis Treatment and Protein Kinase Inhibition by Hydroxystilbenes and Novel Stilbene Derivatives and Analogues | NFKBIA, IKBKB, IKBKE | TRPA1 1740/4885ALDH1A1 3081/4885TSHR 3759/4885 |
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | C5, CYP51A1, DDT | TRPA1 5/4885ALDH1A1 2604/4885TSHR 4291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.