Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 8/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.65 |
| ▸ | ABL1 | P00519 | 3/20 | 0.62 |
| ▸ | BCR | P11274 | 3/20 | 0.62 |
| ▸ | NQO2 | P16083 | 7/20 | 0.61 |
| ▸ | TTR | P02766 | 3/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.61 |
| ▸ | MYC | P01106 | 1/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.53 |
| ▸ | TUBB | P07437 | 2/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576879 | 1.00 | CYP1A1 (0.65) | CYP1A1CYP1B1CYP1A2ABL1BCR | |
| SCHEMBL4576395 | 0.86 | TUBB1 (0.67) | CYP1A1CYP1B1CYP1A2ABL1BCR | |
| SCHEMBL4576391 | 0.86 | TUBB1 (0.67) | CYP1A1CYP1B1CYP1A2ABL1BCR | |
| SCHEMBL11983792 | 0.82 | ALDH1A1 (0.48) | CYP1A1CYP1B1CYP1A2ABCG2CYP3A4 | |
| SCHEMBL919000 | 0.80 | TUBB1 (0.66) | CYP1A1CYP1B1CYP1A2NQO2TUBB4A | |
| SCHEMBL4575925 | 0.80 | NFE2L2 (0.46) | CYP1A1CYP1B1CYP1A2ABL1BCR | |
| SCHEMBL918999 | 0.80 | TUBB1 (0.66) | CYP1A1CYP1B1CYP1A2NQO2TUBB4A | |
| SCHEMBL4575923 | 0.80 | NFE2L2 (0.46) | CYP1A1CYP1B1CYP1A2ABL1BCR | |
| SCHEMBL1743363 | 0.79 | CYP1A1 (1.00) | CYP1A1CYP1B1CYP1A2ABL1BCR | |
| SCHEMBL1743365 | 0.79 | CYP1A1 (1.00) | CYP1A1CYP1B1CYP1A2ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255245-A1 | Anti-Inflammatory and Psoriasis Treatment and Protein Kinase Inhibition by Hydroxystilbenes and Novel Stilbene Derivatives and Analogues | WELICHEM BIOTECH INC. (CA) | 2008-10-16 | — | — | US | disclosed |
| US-7321050-B2 | Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues | WELICHEM BIOTECH INC. (CA) | 2008-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255245-A1 | Anti-Inflammatory and Psoriasis Treatment and Protein Kinase Inhibition by Hydroxystilbenes and Novel Stilbene Derivatives and Analogues | NFKBIA, IKBKB, IKBKE | CYP1A1 2864/4885CYP1B1 2725/4885CYP1A2 2954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.