Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28646842 | 0.91 | ALDH1A1 (0.44) | ALDH1A1TSHRPKMNPC1RAB9A | |
| SCHEMBL15564427 | 0.90 | ALDH1A1 (0.43) | ALDH1A1TSHRPKMNPC1RAB9A | |
| SCHEMBL28638061 | 0.87 | ALDH1A1 (0.42) | ALDH1A1TSHRPKMNPC1RAB9A | |
| SCHEMBL16968209 | 0.86 | ALDH1A1 (0.41) | ALDH1A1TSHRPKMNPC1RAB9A | |
| SCHEMBL12650380 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TSHRPKMNPC1RAB9A | |
| SCHEMBL16968201 | 0.85 | KMT2A (0.44) | ALDH1A1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL15564659 | 0.85 | ALDH1A1 (0.40) | ALDH1A1TSHRPKMNPC1RAB9A | |
| SCHEMBL15563858 | 0.84 | PGR (0.40) | ALDH1A1SMN1; SMN2L3MBTL1KMT2AMAPK8 | |
| SCHEMBL18256164 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TSHRPKMNPC1RAB9A | |
| SCHEMBL16968198 | 0.83 | ALDH1A1 (0.38) | ALDH1A1TSHRSMN1; SMN2MAPK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080167313-A1 | 1,2,4-Triazine Derivatives, Preparation and Use Thereof in Human Therapy | PIERRE FABRE MEDICAMENT (FR) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167313-A1 | 1,2,4-Triazine Derivatives, Preparation and Use Thereof in Human Therapy | CBR3, NOX3, RTN3 | ALDH1A1 2991/4885TSHR 133/4885PKM 2798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.