SCHEMBL4576538

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8638315	0.78	—	—
	SCHEMBL41775	0.78	TSHR (0.67)	TSHRPRSS1PRSS2PRSS3CA1
	SCHEMBL3481703	0.76	LPL (0.52)	TSHRCA2HSD17B10HPGD
	SCHEMBL31672218	0.72	TSHR (0.59)	TSHRPRSS1PRSS2PRSS3CA1
	SCHEMBL11310791	0.69	MKNK1 (0.56)	TSHRPRSS1PRSS2PRSS3CA1
	SCHEMBL260498	0.69	TSHR (0.56)	TSHRPRSS1PRSS2PRSS3CA1
	Formaldehyde SCHEMBL8673672	0.69	TSHR (0.56)	TSHRPRSS1PRSS2PRSS3CA1
	SCHEMBL679970	0.69	MKNK1 (0.56)	TSHRPRSS1PRSS2PRSS3CA1
	SCHEMBL7539245	0.69	CHKA (0.58)	TSHRPRSS1PRSS2PRSS3CA1
	SCHEMBL11318432	0.69	TSHR (0.56)	TSHRPRSS1PRSS2PRSS3CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.