Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | USP1 | O94782 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457626 | 0.87 | GPR119 (0.46) | GPR119POLBOPRD1OPRK1 | |
| SCHEMBL22310762 | 0.78 | POLB (0.51) | GPR119POLB | |
| SCHEMBL26931991 | 0.78 | POLB (0.45) | GPR119POLBOPRD1OPRK1 | |
| SCHEMBL27002699 | 0.77 | GPR119 (0.48) | GPR119POLB | |
| SCHEMBL457651 | 0.77 | GPR119 (0.56) | GPR119 | |
| SCHEMBL29939711 | 0.77 | PKM (0.52) | GPR119 | |
| SCHEMBL24548405 | 0.77 | GPR119 (0.41) | GPR119USP1 | |
| SCHEMBL13351454 | 0.76 | USP2 (0.46) | GPR119OPRD1OPRK1USP1 | |
| SCHEMBL26931893 | 0.76 | PDE4A (0.45) | GPR119POLBOPRD1OPRK1 | |
| SCHEMBL16892078 | 0.75 | CYP3A4 (0.48) | GPR119OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |