Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155331 | 0.80 | MAPT (0.43) | PKMMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL241130 | 0.78 | GPR119 (0.59) | PKMGPR119HDAC1ALDH1A1 | |
| SCHEMBL7402974 | 0.77 | GPR119 (0.64) | PKMGPR119MAPTALDH1A1 | |
| SCHEMBL457656 | 0.77 | GPR119 (0.47) | GPR119 | |
| SCHEMBL25320725 | 0.76 | GPR119 (0.48) | PKMGPR119JAK2JAK1MEN1 | |
| SCHEMBL7376662 | 0.76 | GPR119 (0.70) | PKMGPR119ALDH1A1 | |
| SCHEMBL31330775 | 0.76 | GPR119 (0.54) | PKMGPR119HDAC1ALDH1A1 | |
| SCHEMBL15368794 | 0.76 | USP2 (0.47) | GPR119SMN1; SMN2 | |
| SCHEMBL7401949 | 0.76 | GPR119 (0.54) | GPR119MAPTALDH1A1 | |
| SCHEMBL17762747 | 0.75 | PKM (0.50) | PKMGPR119JAK2JAK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215787-A | Somatostatin receptor 5 antagonists and uses thereof | 中国科学院上海药物研究所 | 2022-10-21 | — | — | CN | disclosed |