Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.50 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 4/20 | 0.33 |
| ▸ | DRD5 | P21918 | 4/20 | 0.33 |
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31538816 | 1.00 | HTR2A (0.50) | HTR2ADRD2HTR2CSLC6A2SLC6A4 | |
| SCHEMBL5837715 | 0.88 | LMNA (0.40) | HTR2AMEN1KMT2A | |
| SCHEMBL233774 | 0.77 | APEX1 (0.42) | HTR2ADRD2HTR2CSLC6A2SLC6A4 | |
| SCHEMBL29415598 | 0.77 | APEX1 (0.42) | HTR2ADRD2HTR2CSLC6A2SLC6A4 | |
| Lithium SCHEMBL31124519 | 0.75 | APEX1 (0.41) | HTR2ADRD2HTR2CSLC6A2SLC6A4 | |
| SCHEMBL5837474 | 0.73 | KDM4E (0.39) | HTR2ADRD2HTR2CSLC6A2SLC6A4 | |
| SCHEMBL15733055 | 0.72 | HTR2A (0.50) | HTR2ADRD2HTR2CSLC6A2SLC6A4 | |
| SCHEMBL30565205 | 0.72 | HTR2A (0.50) | HTR2ADRD2HTR2CSLC6A2SLC6A4 | |
| SCHEMBL29114648 | 0.72 | HTR2A (0.39) | HTR2ADRD2HTR2CSLC6A2SLC6A4 | |
| SCHEMBL5836205 | 0.72 | P2RX4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170121430-A1 | Ziegler-Natta Catalyst Composition And A Process For Its Preparation | RELIANCE INDUSTRIES LIMITED (IN) | 2017-05-04 | — | — | US | claimed |
| EP-1260523-B1 | CATALYST SYSTEM FOR POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS | CHINA PETROCHEMICAL CORP (CN) | 2013-01-23 | — | — | EP | claimed |
| US-7022640-B2 | 1,3-diethers and components and catalysts for the polymerization of olefins, containing said diethers | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2006-04-04 | — | — | US | claimed |
| US-20040235645-A1 | 1,3-Diethers and components and catalysts for the polymerization of olefins, containing said diethers | MORINI GIAMPIERO (IT) | 2004-11-25 | — | — | US | claimed |
| US-6683017-B2 | SOLID CATALYST COMPONENT COMPRISING TITANIUM, MAGNESIUM, HALOGEN AND A 1,3-DIETHER, ORGANIC ALUMINUM COMPOUND, ORGANIC SILICON COMPOUND | CHINA PETRO - CHEMICAL CORPORATION (CN) | 2004-01-27 | — | — | US | claimed |
| EP-1260523-A1 | CATALYST SYSTEM FOR POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS | CHINA PETROCHEMICAL CORPORATION (CN) | 2002-11-27 | — | — | EP | claimed |
| US-20010025006-A1 | Catalyst system for the (co) polymerization of olefins | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, SINOPEC (CN) | 2001-09-27 | — | — | US | claimed |
| EP-0728724-A1 | Diethers suitable for use in the preparation of Ziegler-Natta catalysts | MONTELL NORTH AMERICA INC. (US) | 1996-08-28 | — | — | EP | claimed |
| US-10308563-B2 | Process for producing ethylene oligomers | HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) | 2019-06-04 | — | — | US | disclosed |
| US-20180170827-A1 | PROCESS FOR PRODUCING ETHYLENE OLIGOMERS | HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) | 2018-06-21 | — | — | US | disclosed |
| US-20180169642-A1 | CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION AND METHOD FOR PRODUCING ETHYLENE OLIGOMERIZATION USING THE SAME | HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) | 2018-06-21 | — | — | US | disclosed |
| EP-1472293-B1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEM CORP (CN) | 2017-04-26 | — | — | EP | disclosed |
| EP-1746110-B1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF | CHINA PETROLEUM & CHEMICAL (CN) | 2015-03-11 | — | — | EP | disclosed |
| EP-1609805-B1 | COMPLEX SUPPORT SUITABLE FOR PROPYLENE POLYMERIZATION CATALYST, A CATALYST COMPONENT AND CATALYST CONTAINING THE SAME | CHINA PETROLEUM & CHEMICAL (CN) | 2012-10-17 | — | — | EP | disclosed |
| US-20010025006-A1 | Catalyst system for the (co) polymerization of olefins | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, SINOPEC (CN) | 2001-09-27 | — | — | US | disclosed |
| EP-0728769-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1998-08-19 | — | — | EP | disclosed |
| US-5723400-A | Process for the preparation of a solid catalyst component suitable for the polymerization of olefins which includes at least two additions of an electron donor | MONTELL NORTH AMERICA INC. (US) | 1998-03-03 | — | — | US | disclosed |
| EP-0728770-A1 | Process for the preparation of solid catalyst components for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1996-08-28 | — | — | EP | disclosed |
| EP-0728724-A1 | Diethers suitable for use in the preparation of Ziegler-Natta catalysts | MONTELL NORTH AMERICA INC. (US) | 1996-08-28 | — | — | EP | disclosed |
| EP-0728769-A1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1996-08-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308563-B2 | Process for producing ethylene oligomers | OXER1, HAO2, ORC3 | HTR2A 834/4885DRD2 1989/4885HTR2C 668/4885 |
| US-20180169642-A1 | CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION AND METHOD FOR PRODUCING ETHYLENE OLIGOMERIZATION USING THE SAME | HACL2, HAO2, MSMO1 | HTR2A 1126/4885DRD2 2096/4885HTR2C 834/4885 |
| US-20180170827-A1 | PROCESS FOR PRODUCING ETHYLENE OLIGOMERS | OXER1, HAO2, ORC3 | HTR2A 834/4885DRD2 1989/4885HTR2C 668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.