SCHEMBL1743365

SCHEMBL1743365

COc1cc(C=Cc2cc(OC)cc(OC)c2)cc(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 8/20 1.00
CYP1B1 Q16678 8/20 1.00
NQO2 P16083 6/20 0.77
CYP1A2 P05177 5/20 0.77
ABL1 P00519 4/20 0.77
BCR P11274 4/20 0.77
TTR P02766 3/20 0.77
ALOX5 P09917 3/20 0.77
ESR1 P03372 2/20 0.77
ABCB1 P08183 2/20 0.77
CYP19A1 P11511 2/20 0.77
PTGS2 P35354 2/20 0.77
TUBB4A P04350 1/20 0.77
TUBB P07437 1/20 0.77
TUBA3C P0DPH7 1/20 0.77
AHR P35869 1/20 0.77
TUBA1B P68363 1/20 0.77
TUBA4A P68366 1/20 0.77
TUBB4B P68371 1/20 0.77
TUBB3 Q13509 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1743363 1.00 CYP1A1 (1.00) CYP1A1CYP1B1NQO2CYP1A2ABL1
SCHEMBL16362233 0.88 CYP1A1 (0.77) CYP1A1CYP1B1NQO2CYP1A2ABL1
8Z-3,4',5-Trimethoxystilbene SCHEMBL1006207 0.88 CYP1A1 (1.00) CYP1A1CYP1B1NQO2CYP1A2ABL1
Trismethoxyresveratrol SCHEMBL918740 0.88 CYP1A1 (1.00) CYP1A1CYP1B1NQO2CYP1A2ABL1
Trismethoxyresveratrol SCHEMBL918739 0.88 CYP1A1 (1.00) CYP1A1CYP1B1NQO2CYP1A2ABL1
SCHEMBL5784563 0.87 CYP1A1 (0.76) CYP1A1CYP1B1NQO2CYP1A2ABL1
SCHEMBL13841258 0.87 CYP1A1 (0.76) CYP1A1CYP1B1NQO2CYP1A2ABL1
SCHEMBL5784566 0.87 CYP1A1 (0.76) CYP1A1CYP1B1NQO2CYP1A2ABL1
3,5-O-Dimethylpinosylvin SCHEMBL918727 0.86 KDM4E (0.79) CYP1A1CYP1B1NQO2CYP1A2ABL1
3,5-O-Dimethylpinosylvin SCHEMBL918726 0.86 KDM4E (0.79) CYP1A1CYP1B1NQO2CYP1A2ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313010-A1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 Szekeres, Thomas (AT) 2024-02-07 EP claimed
WO-2022200086-A1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 SZEKERES THOMAS (AT) 2022-09-29 WO claimed
EP-1654210-B1 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS SZEKERES THOMAS (AT) 2008-07-30 EP claimed
US-20240166587-A1 SARS-CoV-2 inhibitors - artificial compounds SZEKERES THOMAS (AT) 2024-05-23 US disclosed
EP-4313010-A1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 Szekeres, Thomas (AT) 2024-02-07 EP disclosed
WO-2022200086-A1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 SZEKERES THOMAS (AT) 2022-09-29 WO disclosed
US-9187591-B1 Polyphenols and high-performance resins from syringaldehyde THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-11-17 US disclosed
US-9127115-B1 Polyphenols and high-performance resins from syringaldehyde THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-09-08 US disclosed
US-9051414-B1 Polyphenols and high-performance resins from syringaldehyde The United States of America as Represented by the Secretary of he Navy (US) 2015-06-09 US disclosed
US-9018314-B1 Polyphenols and high-performance resins from syringaldehyde THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-04-28 US disclosed
US-8993689-B1 Polyphenols and high-performance resins from syringaldehyde THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-03-31 US disclosed
US-8921614-B1 Selective deoxygenation of hydroxybenzaldehydes THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2014-12-30 US disclosed
US-8835659-B2 Polysubstituted benzofurans and medicinal applications thereof IKERCHEM, S.L. (ES) 2014-09-16 US disclosed
US-20130217730-A1 POLYSUBSTITUTED BENZOFURANS AND MEDICINAL APPLICATIONS THEREOF IKERCHEM, S.L. (ES) 2013-08-22 US disclosed
EP-2388255-A1 Polysubstituted benzofurans and medicinal applications thereof Ikerchem, S.L. (ES) 2011-11-23 EP disclosed
US-8038466-B1 Power receptacle with enlarged heat dissipation path formed on mating face and power connector assembly thereof ALLTOP ELECTRONICS (SUZHOU) CO., LTD (CN) 2011-10-18 US disclosed
EP-1654210-B1 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS SZEKERES THOMAS (AT) 2008-07-30 EP disclosed
US-20070191627-A1 Stilbene derivatives and their use in medicaments SZEKERES THOMAS 2007-08-16 US disclosed
EP-1654210-A2 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS Szekeres, Thomas (AT) 2006-05-10 EP disclosed
WO-2005016860-A2 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS SZEKERES THOMAS (AT) 2005-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240166587-A1 SARS-CoV-2 inhibitors - artificial compounds ACE2, ACE, FURIN CYP1A1 281/4885CYP1B1 622/4885NQO2 645/4885
US-20130217730-A1 POLYSUBSTITUTED BENZOFURANS AND MEDICINAL APPLICATIONS THEREOF AGER, TFEB, FPGS CYP1A1 349/4885CYP1B1 107/4885NQO2 324/4885
US-20070191627-A1 Stilbene derivatives and their use in medicaments PTGS2, PTGS1, PTGER2 CYP1A1 371/4885CYP1B1 275/4885NQO2 693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.