SCHEMBL4576969

SCHEMBL4576969

CC1=C([Ti]C2=CC=CC2)CC(c2ccccc2)=C1c1ccccc1.[H-].[H-]

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 2/20 0.31
PTGS2 P35354 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4576439 0.83 PTGS2 (0.38) PTGS1PTGS2
Biphenyl SCHEMBL820134 0.73 ALDH1A1 (0.39)
SCHEMBL4577222 0.71
Biphenyl SCHEMBL27460408 0.70 ALDH1A1 (0.36)
SCHEMBL27949026 0.69 PTGS2 (0.42) PTGS1PTGS2
SCHEMBL4576973 0.69 PTGS1 (0.31) PTGS1PTGS2
Benzene SCHEMBL9168412 0.67
Iodobenzene SCHEMBL6918393 0.67
SCHEMBL8578202 0.66
SCHEMBL4576021 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448568-A4 DICOPS CONTAINING ACETYLENIC SUBSTITUENTS EXXONMOBIL CHEM PATENTS INC (US) 2008-02-13 EP disclosed
EP-1448568-A2 DICOPS CONTAINING ACETYLENIC SUBSTITUENTS ExxonMobil Chemical Patents Inc. (US) 2004-08-25 EP disclosed
WO-2003040070-A2 DICOPS CONTAINING ACETYLENIC SUBSTITUENTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-05-15 WO disclosed