Biphenyl

Biphenyl

SCHEMBL820134

C1=CCC([Ti]C2=CC=CC2)=C1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
SLC22A2 O15244 1/20 0.33
SLC22A1 O15245 1/20 0.33
SLC22A3 O75751 1/20 0.33
SLC6A4 P31645 1/20 0.33
CYP1A2 P05177 2/20 0.31
MAPK1 P28482 1/20 0.31
CYP3A4 P08684 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NOTUM Q6P988 1/20 0.31
MMP3 P08254 1/20 0.31
BCL2L1 Q07817 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
CYP1A1 P04798 1/20 0.30
CYP1B1 Q16678 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27460408 0.96 ALDH1A1 (0.36) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Benzene SCHEMBL9168412 0.89
Iodobenzene SCHEMBL6918393 0.83
Bromobenzene SCHEMBL6916259 0.83 ALDH1A1 (0.44) ALDH1A1MAPK1TDP1
Chlorobenzene SCHEMBL819538 0.83 TSHR (0.44) CYP1A2
SCHEMBL4480097 0.83
SCHEMBL820172 0.83
SCHEMBL8578202 0.83
SCHEMBL819650 0.82 MAOA (0.38) ALDH1A1TAAR1HSD17B10TDP1MAOA
Diphenylether SCHEMBL27491868 0.82 LTA4H (0.46) SLC6A4MAOAMAOBNPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 439 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100137525-A1 Catalyst composition for hydrogenation and their use for hydrogenation conjugated diene polymer CHI-MEI CORPORATION 2010-06-03 US claimed
US-20080171653-A1 Catalyst composition for hydrogenation and their use for hydrogenation conjugated diene polymer CHI-MEI CORPORATION 2008-07-17 US claimed
US-6982236-B2 Process to polymerize olefins UNIVATION TECHNOLOGIES, LLC (US) 2006-01-03 US claimed
US-6897273-B2 Catalyst composition, method of polymerization and polymer therefrom UNIVATION TECHNOLOGIES, LLC (US) 2005-05-24 US claimed
EP-1392743-A2 CATALYST COMPOSITION, METHOD OF POLYMERIZATION AND POLYMER THEREFROM Univation Technologies LLC (US) 2004-03-03 EP claimed
US-20040039138-A1 Catalyst preparation method WENZEL TIMOTHY T (US) 2004-02-26 US claimed
US-6656866-B2 Metallocene and non-metallocene, homogeneous catalysts, particularly for use in the economical gas and slurry phase processes; spray dried olefin polymerization catalysts UNIVATION TECHNOLOGIES, LLC 2003-12-02 US claimed
US-20030207762-A9 CATALYST PREPARATION METHOD UNIVATION TECHNOLOGIES, LLC 2003-11-06 US claimed
EP-1358216-A2 START-UP PROCEDURE FOR MULTIPLE CATALYST POLYMERIZATION SYSTEMS Univation Technologies LLC (US) 2003-11-05 EP claimed
US-6620894-B2 Calibration; using coordination catalyst UNIVATION TECHNOLOGIES, LLC 2003-09-16 US claimed
US-4808561-A Supported polymerization catalyst EXXON CHEMICAL PATENTS INC. (US) 1989-02-28 US claimed
US-4791180-A New polymerization catalyst EXXON CHEMICAL PATENTS INC. (US) 1988-12-13 US claimed
US-4752597-A New polymerization catalyst EXXON CHEMICAL PATENTS INC. (US) 1988-06-21 US claimed
WO-1988002008-A1 NEW SUPPORTED POLYMERIZATION CATALYST EXXON CHEMICAL PATENTS, INC. (US) 1988-03-24 WO claimed
EP-0260130-A1 New supported polymerization catalyst EXXON CHEMICAL PATENTS INC. (US) 1988-03-16 EP claimed
EP-0245482-A1 SUPPORTED POLYMERIZATION CATALYST EXXON CHEMICAL PATENTS INC. (US) 1987-11-19 EP claimed
US-4701432-A CYCLOPENTA DIENYL-CONTAINING METAL COMPOUNDS AND A NON-CYCLOPENTA DIENYL-CONTAINING TRANSITION METAL COMPOUND; COORDINATION CATALYSTS; ETHYLENE HOMO- AND COPOLYMERS EXXON CHEMICAL PATENTS INC. (US) 1987-10-20 US claimed
EP-0232595-A1 Supported polymerization catalyst (P-1180) EXXON CHEMICAL PATENTS INC. (US) 1987-08-19 EP claimed
WO-1987002991-A1 SUPPORTED POLYMERIZATION CATALYST EXXON CHEMICAL PATENTS, INC. (US) 1987-05-21 WO claimed
EP-0206794-A1 Supported polymerization catalyst EXXON CHEMICAL PATENTS INC. (US) 1986-12-30 EP claimed