Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.47 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | GNPAT | O15228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17715158 | 1.00 | MAPT (0.52) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL28015219 | 0.86 | FOLH1 (0.48) | FOLH1NAALAD2RIMKLASLC1A1TSHR | |
| SCHEMBL18849724 | 0.85 | FOLH1 (0.47) | FOLH1NAALAD2RIMKLASLC1A1TSHR | |
| SCHEMBL463421 | 0.85 | CA12 (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL468764 | 0.85 | CA12 (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL21274418 | 0.84 | L3MBTL1 (0.58) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL21274419 | 0.84 | L3MBTL1 (0.58) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL11124589 | 0.84 | L3MBTL1 (0.58) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL13379936 | 0.83 | FOLH1 (0.46) | FOLH1NAALAD2RIMKLASLC1A1TSHR | |
| SCHEMBL10045845 | 0.82 | SMN1; SMN2 (0.53) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284872-A | Nitrato alkanoic acid derivatives, methods for their production, pharmaceutical compositions containing the derivatives and medicinal uses thereof | SCHWARZ PHARMA AG (DE) | 1994-02-08 | — | — | US | claimed |
| WO-2019202611-A1 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | METROCHEM API PVT (IN) | 2019-10-24 | — | — | WO | disclosed |
| EP-1414432-A4 | METHODS OF USE FOR NOVEL SULFUR CONTAINING ORGANIC NITRATE COMPOUNDS | NITROMED INC (US) | 2008-01-09 | — | — | EP | disclosed |
| US-20040152753-A1 | Methods of use for novel sulfur containing organic nitrate compounds | NITROMED, INC. | 2004-08-05 | — | — | US | disclosed |
| EP-1414432-A2 | METHODS OF USE FOR NOVEL SULFUR CONTAINING ORGANIC NITRATE COMPOUNDS | Nitromed, Inc. (US) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003013432-A2 | METHODS OF USE FOR NOVEL SULFUR CONTAINING ORGANIC NITRATE COMPOUNDS | NITROMED, INC. (US) | 2003-02-20 | — | — | WO | disclosed |
| US-5284872-A | Nitrato alkanoic acid derivatives, methods for their production, pharmaceutical compositions containing the derivatives and medicinal uses thereof | SCHWARZ PHARMA AG (DE) | 1994-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152753-A1 | Methods of use for novel sulfur containing organic nitrate compounds | PTGS2, NOS2, PTGS1 | MAPT 1688/4885KDM4E 4241/4885THRB 3394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.