SCHEMBL4577302

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4577925	0.88	DNM1 (0.61)	DNM1ACKR3CASP2PAOXTSHR
	SCHEMBL24412648	0.83	DNM1 (0.65)	DNM1ALDH1A1CASP2PAOXTSHR
	SCHEMBL1387288	0.83	DNM1 (0.61)	DNM1ACKR3ALDH1A1LGALS1
	SCHEMBL7140311	0.83	DNM1 (0.61)	DNM1ACKR3ALDH1A1TERTCASP2
	SCHEMBL4577306	0.83	DNM1 (0.55)	DNM1ALDH1A1PAOXNAAA
	SCHEMBL8956597	0.83	DNM1 (0.52)	DNM1ACKR3ALDH1A1LGALS1TERT
	SCHEMBL12946153	0.81	DNM1 (0.50)	DNM1ACKR3ALDH1A1LGALS1TERT
	SCHEMBL8956620	0.79	DNM1 (0.56)	DNM1ACKR3CASP2PAOXTSHR
	SCHEMBL8975550	0.79	DNM1 (0.49)	DNM1ACKR3ALDH1A1LGALS1TERT
	SCHEMBL9501556	0.79	DNM1 (0.61)	DNM1CASP2PAOXTSHRNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.