Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 15/20 | 0.51 |
| ▸ | RARG | P13631 | 12/20 | 0.51 |
| ▸ | RARA | P10276 | 11/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382090 | 0.83 | RARA (0.48) | RARBRARGRARANPC1RAB9A | |
| SCHEMBL382380 | 0.79 | RARB (0.42) | RARBRARGRARANPC1RAB9A | |
| SCHEMBL382740 | 0.79 | RARG (0.61) | RARBRARGRARA | |
| SCHEMBL4576451 | 0.76 | RARG (0.69) | RARBRARGRARADHODH | |
| SCHEMBL382994 | 0.76 | RARA (0.51) | RARBRARGRARAKDM4ENPC1 | |
| SCHEMBL382393 | 0.72 | RARG (0.55) | RARBRARGRARAKDM4EALDH1A1 | |
| SCHEMBL382549 | 0.71 | RARG (0.60) | RARBRARGRARA | |
| SCHEMBL3439183 | 0.71 | RARG (0.63) | RARBRARGRARA | |
| SCHEMBL382163 | 0.70 | HRH3 (0.43) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL5855140 | 0.69 | RARB (0.64) | RARBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015246-A1 | Novel ligands that modulate RAR receptors and pharmaceutical/cosmetic compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015246-A1 | Novel ligands that modulate RAR receptors and pharmaceutical/cosmetic compositions comprised thereof | RARB, RARA, RARG | RARB 1/4885RARG 3/4885RARA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.