Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 3/20 | 0.30 |
| ▸ | NOS1 | P29475 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanine SCHEMBL2636585 | 0.94 | KDM4E (0.38) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Guanine SCHEMBL2499472 | 0.92 | KDM4E (0.50) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Guanine SCHEMBL17542295 | 0.91 | ATAD2 (0.36) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Adenine SCHEMBL2558877 | 0.89 | CRBN (0.50) | LMNADYRK1ACRBNMAP4K4PNP | |
| Guanine SCHEMBL21223789 | 0.88 | ALDH1A1 (0.50) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Guanine SCHEMBL1831275 | 0.88 | ALDH1A1 (0.50) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Guanine SCHEMBL15718980 | 0.86 | KDM4E (0.33) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Guanine SCHEMBL9468221 | 0.85 | KDM4E (0.32) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Guanine SCHEMBL13516878 | 0.85 | KDM4E (0.44) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Guanine SCHEMBL1730016 | 0.85 | DYRK1A (0.42) | KDM4EALDH1A1LMNAGLAPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319026-B2 | Amino acid-producing bacteria and a process for preparing L-amino acids | DEGUSSA AG (DE) | 2008-01-15 | — | — | US | disclosed |
| EP-1481075-A2 | AMINO ACID-PRODUCING BACTERIA AND A PROCESS FOR PREPARING L-AMINO ACIDS | Degussa AG (DE) | 2004-12-01 | — | — | EP | disclosed |
| US-20040082040-A1 | Amino acid-producing bacteria and a process for preparing L-amino acids | DEGUSSA AG | 2004-04-29 | — | — | US | disclosed |
| WO-2003074719-A2 | AMINO ACID-PRODUCING BACTERIA AND A PROCESS FOR PREPARING L-AMINO ACIDS | DEGUSSA AG (DE) | 2003-09-12 | — | — | WO | disclosed |