Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 2/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL8469554 | 0.90 | ALDH1A1 (0.43) | CRBNMAP4K4PNPPI4KAPI4K2B | |
| Guanine SCHEMBL4577520 | 0.89 | KDM4E (0.43) | CRBNMAP4K4PNPLMNAXDH | |
| Adenine SCHEMBL7520981 | 0.85 | CRBN (0.36) | CRBNMAP4K4 | |
| Guanine SCHEMBL2636585 | 0.83 | KDM4E (0.38) | CRBNMAP4K4PNPLMNADYRK1A | |
| Adenine SCHEMBL6227731 | 0.82 | ATAD2 (0.37) | CRBNMAP4K4 | |
| Adenine SCHEMBL8110 | 0.79 | PI4KA (0.48) | MAP4K4PNPPI4KAPI4K2BPI4K2A | |
| Adenine SCHEMBL3416954 | 0.79 | PI4KA (0.48) | MAP4K4PNPPI4KAPI4K2BPI4K2A | |
| Adenine SCHEMBL3414603 | 0.79 | PI4KA (0.48) | MAP4K4PNPPI4KAPI4K2BPI4K2A | |
| Adenine SCHEMBL3413247 | 0.79 | PI4KA (0.48) | MAP4K4PNPPI4KAPI4K2BPI4K2A | |
| Adenine SCHEMBL2558881 | 0.78 | PI4KA (0.63) | CRBNPNPPI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652528-A1 | ACTIVATED CARBON INFUSION SOLUTION, PREPARATION METHOD THEREFOR AND USE THEREOF FOR THE MANUFACTURE OF DRUG FOR TREATING CANCER | Chen, Xiaochuan (CN) | 2006-05-03 | — | — | EP | claimed |
| US-20050123613-A1 | Activated carbon infusion solution, preparation method therefor and use thereof for the manufacture of drug for treating cancer | CHEN XIAOCHUAN (CN) | 2005-06-09 | — | — | US | claimed |
| WO-2011130385-A1 | BIOMARKERS FOR HEPATOCELLULAR CANCER | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC | 2011-10-20 | — | — | WO | disclosed |
| US-20090258794-A1 | APOPTOSIS METHODS, GENES AND PROTEINS | MORVUS TECHNOLOGY LTD (GB) | 2009-10-15 | — | — | US | disclosed |
| EP-1984393-A2 | APOPTOSIS METHODS, GENES AND PROTEINS | Morvus Technology Ltd. (GB) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007093807-A2 | APOPTOSIS METHODS, GENES AND PROTEINS | MORVUS TECHNOLOGY LIMITED (GB) | 2007-08-23 | — | — | WO | disclosed |
| EP-1652528-A1 | ACTIVATED CARBON INFUSION SOLUTION, PREPARATION METHOD THEREFOR AND USE THEREOF FOR THE MANUFACTURE OF DRUG FOR TREATING CANCER | Chen, Xiaochuan (CN) | 2006-05-03 | — | — | EP | disclosed |
| US-20050123613-A1 | Activated carbon infusion solution, preparation method therefor and use thereof for the manufacture of drug for treating cancer | CHEN XIAOCHUAN (CN) | 2005-06-09 | — | — | US | disclosed |
| US-4184271-A | Molecular model | BARNETT JAMES W JR | 1980-01-22 | — | — | US | disclosed |