SCHEMBL4577654

SCHEMBL4577654

CN1CC(=O)N(C)C1=O.NC(=O)NC(N)=O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.35
ALDH1A1 P00352 1/20 0.34
RECQL P46063 1/20 0.34
CRBN Q96SW2 1/20 0.33
XIAP P98170 1/20 0.31
BIRC2 Q13490 1/20 0.31
GFER P55789 1/20 0.30
BRD4 O60885 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21387942 0.81 PLA2G7 (0.34) HDAC6ALDH1A1RECQLCRBNBRD4
SCHEMBL22070 0.81
Hydrochloric Acid SCHEMBL28447867 0.79 PLA2G7 (0.35) HDAC6ALDH1A1RECQLCRBNBRD4
SCHEMBL1685396 0.79 PLA2G7 (0.35) HDAC6ALDH1A1RECQLCRBNBRD4
Bromide SCHEMBL28907673 0.79 PLA2G7 (0.35) HDAC6ALDH1A1RECQLCRBNBRD4
Formaldehyde SCHEMBL3082020 0.77 PLA2G7 (0.34) HDAC6ALDH1A1RECQLCRBNBRD4
Bromide SCHEMBL4894442 0.77 PLA2G7 (0.34) HDAC6ALDH1A1RECQLCRBNBRD4
Phenol SCHEMBL11576606 0.68 PLA2G7 (0.44) ALDH1A1BRD4
SCHEMBL11726691 0.65
SCHEMBL13204551 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080292886-A1 ADHESIVE FORMULATIONS CONTAINING UREA ADDITIVES, METHODS OF FORMING PLYWOOD THEREWITH, AND PLYWOOD PRODUCTS MADE THEREBY HERCULES INC. (US) 2008-11-27 US disclosed
WO-2008118741-A1 ADHESIVE, FORMULATIONS CONTAINING UREA ADDITIVES, METHODS OF FORMING PLYWOOD THEREWITH, AND PLYWOOD PRODUCTS MADE THEREBY HERCULES INC. (US) 2008-10-02 WO disclosed