Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 6/20 | 0.65 |
| ▸ | MMP2 | P08253 | 5/20 | 0.65 |
| ▸ | ITGAV | P06756 | 5/20 | 0.59 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.55 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27737068 | 0.95 | MMP9 (0.60) | MMP9MMP2ITGAVSLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL28193637 | 0.94 | MMP2 (0.59) | MMP9MMP2ITGAVSLC1A3SLC1A2 | |
| SCHEMBL11207292 | 0.88 | RECQL (0.52) | MMP9MMP2ITGAVSLC1A3SLC1A2 | |
| SCHEMBL600044 | 0.87 | ITGAV (0.62) | MMP9MMP2ITGAVSLC1A3SLC1A2 | |
| SCHEMBL28658079 | 0.86 | MMP2 (0.49) | MMP9MMP2ITGAVSLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL29175312 | 0.85 | MMP2 (0.48) | MMP9MMP2ITGAVSLC1A3SLC1A2 | |
| SCHEMBL7286164 | 0.84 | MMP2 (0.50) | MMP9MMP2ITGAVSLC1A3SLC1A2 | |
| SCHEMBL27465967 | 0.84 | MMP2 (0.50) | MMP9MMP2ITGAVSLC1A3SLC1A2 | |
| SCHEMBL1509340 | 0.83 | ITGAV (0.63) | MMP9MMP2ITGAVSLC1A3SLC1A2 | |
| SCHEMBL1509337 | 0.83 | ITGAV (0.63) | MMP9MMP2ITGAVSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4243869-A1 | BI-SPECIFIC ANTIBODIES COMPRISING ANTI-CD137 BINDING MOLECULES | Lyvgen Biopharma Holdings Limited (KY) | 2023-09-20 | — | — | EP | disclosed |
| EP-4048701-A1 | ANTI-CD40 BINDING MOLECULES AND BI-SPECIFIC ANTIBODIES COMPRISING SUCH | Lyvgen Biopharma Holdings Limited (KY) | 2022-08-31 | — | — | EP | disclosed |
| WO-2022103780-A1 | BI-SPECIFIC ANTIBODIES COMPRISING ANTI-CD137 BINDING MOLECULES | LYVGEN BIOPHARMA HOLDINGS LIMITED (KY) | 2022-05-19 | — | — | WO | disclosed |
| WO-2021081303-A1 | ANTI-CD40 BINDING MOLECULES AND BI-SPECIFIC ANTIBODIES COMPRISING SUCH | Lyvgen Biopharma (Suzhou) Co., Ltd. (CN) | 2021-04-29 | — | — | WO | disclosed |
| EP-3240570-A1 | BISPECIFIC ANTIBODIES AGAINST PLASMA KALLIKREIN AND FACTOR XII | Dyax Corp. (US) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016109774-A1 | BISPECIFIC ANTIBODIES AGAINST PLASMA KALLIKREIN AND FACTOR XII | DYAX CORP. (US) | 2016-07-07 | — | — | WO | disclosed |
| EP-2640745-A2 | ANTIBODY DERIVATIVES | Allozyne, Inc. (US) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012032181-A9 | ANTIBODY DERIVATIVES | ALLOZYNE, INC (US) | 2013-06-13 | — | — | WO | disclosed |
| WO-2012032181-A2 | NOVEL ANTIBODY DERIVATIVES | ALLOZYNE, INC (US) | 2012-03-15 | — | — | WO | disclosed |