Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | ITGAV | P06756 | 3/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27465967 | 1.00 | MMP2 (0.50) | MMP2MMP9ITGAVSLC1A3SLC1A2 | |
| SCHEMBL28658079 | 0.88 | MMP2 (0.49) | MMP2MMP9ITGAVSLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL29175312 | 0.87 | MMP2 (0.48) | MMP2MMP9ITGAVSLC1A3SLC1A2 | |
| SCHEMBL457771 | 0.84 | MMP9 (0.65) | MMP2MMP9ITGAVSLC1A3SLC1A2 | |
| SCHEMBL27737068 | 0.83 | MMP9 (0.60) | MMP2MMP9ITGAVSLC1A3SLC1A2 | |
| SCHEMBL1305743 | 0.82 | MMP2 (0.56) | MMP2MMP9SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1305745 | 0.82 | MMP2 (0.56) | MMP2MMP9SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11207292 | 0.82 | RECQL (0.52) | MMP2MMP9ITGAVSLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL28193637 | 0.82 | MMP2 (0.59) | MMP2MMP9ITGAVSLC1A3SLC1A2 | |
| SCHEMBL1469951 | 0.80 | POLB (0.52) | MMP2MMP9ITGAVSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263903-A1 | Method for preparing specific inhibitors of virus-specified proteases | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-04-20 | — | — | EP | disclosed |
| EP-0263214-A1 | Tetrapeptide methyl ketone inhibitors of viral proteases | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-04-13 | — | — | EP | disclosed |
| EP-0263202-A1 | Inhibition of viral protease activity by peptide halomethyl ketones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-04-13 | — | — | EP | disclosed |
| US-4652552-A | ENZYME INHIBITORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-03-24 | — | — | US | disclosed |
| US-4644055-A | HALOMETHYL KETONE OR METHYL KETONE COVALENTLY LINKED TO PEPTIDE SEQUENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-02-17 | — | — | US | disclosed |
| US-4636492-A | ENZYME INHIBITORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |