SCHEMBL4577970

SCHEMBL4577970

CCCC(O)CC(O)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
LMNA P02545 1/20 0.36
SPHK1 Q9NYA1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1984188 0.84 TSHR (0.36) TSHRLMNASPHK1
SCHEMBL3687764 0.82 METAP1 (0.35) TSHRLMNASPHK1
SCHEMBL6433370 0.80 LMNA (0.38) TSHRLMNASPHK1
SCHEMBL28576046 0.80 TSHR (0.38) TSHRLMNA
SCHEMBL3096199 0.80 TSHR (0.38) TSHRLMNA
SCHEMBL3096192 0.80 TSHR (0.38) TSHRLMNA
SCHEMBL16153750 0.80 TSHR (0.38) TSHRLMNA
SCHEMBL1991229 0.79 THRB (0.46)
SCHEMBL13354686 0.78 SPHK1 (0.35) SPHK1
SCHEMBL110741 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104177521-B Prepare method and the catalyst of solid catalyst component for olefine polymerization 中国石油化工股份有限公司 2016-08-17 CN claimed
EP-1472293-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2017-04-26 EP disclosed
US-7388061-B2 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 US disclosed
EP-1472293-A4 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2008-01-16 EP disclosed
EP-1478617-A4 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2006-04-19 EP disclosed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US disclosed
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CHINA PETROLEUM & CHEMICAL (CN) 2005-05-05 US disclosed
EP-1478617-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-24 EP disclosed
EP-1472293-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-03 EP disclosed
WO-2003068828-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 WO disclosed
WO-2003068723-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 WO disclosed
EP-0631574-A4 PRODUCING ISOCYANATE DIMERS USING POLYMER-BOUND CATALYSTS. OLIN CORP (US) 1996-04-17 EP disclosed
EP-0629193-A4 PRODUCING ISOCYANATE TRIMERS USING POLYMER-BOUND CATALYSTS. 1995-01-11 EP disclosed
EP-0631574-A1 PRODUCING ISOCYANATE DIMERS USING POLYMER-BOUND CATALYSTS OLIN CORPORATION (US) 1995-01-04 EP disclosed
EP-0629193-A1 PRODUCING ISOCYANATE TRIMERS USING POLYMER-BOUND CATALYSTS OLIN CORPORATION (US) 1994-12-21 EP disclosed
US-5315004-A Process for producing uretidione dimers of isocyanates using catalysts which are bound to inorganic matrices OLIN CORPORATION (US) 1994-05-24 US disclosed
WO-1993019049-A1 PRODUCING ISOCYANATE DIMERS USING POLYMER-BOUND CATALYSTS OLIN CORPORATION (US) 1993-09-30 WO disclosed
WO-1993018014-A1 PRODUCING ISOCYANATE TRIMERS USING POLYMER-BOUND CATALYSTS OLIN CORPORATION (US) 1993-09-16 WO disclosed
US-5221743-A Process for producing isocyanurates by cyclotrimerizing isocyanates using polymer-bound catalysts OLIN CORPORATION (US) 1993-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CBR3, CBR1, OXER1 TSHR 921/4885LMNA 4205/4885SPHK1 1601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.