Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687764 | 0.88 | METAP1 (0.35) | LMNATSHRSPHK1METAP1 | |
| SCHEMBL16882890 | 0.82 | TSHR (0.40) | TSHR | |
| SCHEMBL28946275 | 0.82 | TSHR (0.40) | TSHR | |
| SCHEMBL12834265 | 0.81 | LMNA (0.38) | LMNATSHRSPHK1METAP1 | |
| SCHEMBL1984188 | 0.80 | TSHR (0.36) | LMNATSHRSPHK1 | |
| SCHEMBL4577970 | 0.80 | TSHR (0.36) | LMNATSHRSPHK1 | |
| SCHEMBL104882 | 0.79 | — | — | |
| SCHEMBL15887293 | 0.79 | — | — | |
| SCHEMBL14928533 | 0.79 | — | — | |
| SCHEMBL7591144 | 0.78 | LMNA (0.38) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288452-A1 | Aliphatic polyester composition, films and multilayer films produced therefrom | TOHCELLO CO., LTD. (JP) | 2005-12-29 | — | — | US | disclosed |
| EP-1115925-B1 | POLYESTERS CONTAINING NEOPENTYL GLYCOL AND FIBERS FORMED THEREFROM | EASTMAN CHEM CO (US) | 2005-08-03 | — | — | EP | disclosed |