SCHEMBL4578624

SCHEMBL4578624

C#COC(=O)c1ccc(-c2ccccc2)cc1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 4/20 0.51
HNF4A P41235 2/20 0.51
MCL1 Q07820 2/20 0.51
DHFR P00374 1/20 0.51
DCLRE1A Q6PJP8 1/20 0.46
DCLRE1B Q9H816 1/20 0.46
PTPN1 P18031 3/20 0.44
ACLY P53396 2/20 0.42
IKBKB O14920 1/20 0.41
AKR1C2 P52895 3/20 0.41
AKR1C1 Q04828 3/20 0.41
AKR1C4 P17516 1/20 0.41
AKR1C3 P42330 1/20 0.41
GSTA1 P08263 1/20 0.41
CDC25B P30305 1/20 0.40
ATM Q13315 1/20 0.40
PTPN2 P17706 1/20 0.40
PTPN6 P29350 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2747742 0.86 ACMSD (0.46) ACMSDHNF4AMCL1DHFRDCLRE1A
SCHEMBL3804667 0.82 ACMSD (0.59) ACMSDHNF4AMCL1DHFRDCLRE1A
SCHEMBL2747010 0.81 ALDH1A1 (0.56) AKR1C3CDC25BATM
SCHEMBL15537502 0.79 NPC1 (0.41) AKR1C3CDC25B
SCHEMBL30616786 0.79 ACMSD (0.70) ACMSDHNF4AMCL1DHFRDCLRE1A
SCHEMBL68982 0.79 ACMSD (0.70) ACMSDHNF4AMCL1DHFRDCLRE1A
SCHEMBL11476890 0.78 ACMSD (0.54) ACMSDHNF4AMCL1DHFRDCLRE1A
Hydrochloric Acid SCHEMBL11162468 0.77 ACMSD (0.68) ACMSDHNF4AMCL1DHFRDCLRE1A
Methane SCHEMBL29008389 0.77 ACMSD (0.68) ACMSDHNF4AMCL1DHFRDCLRE1A
Water SCHEMBL29008379 0.77 ACMSD (0.68) ACMSDHNF4AMCL1DHFRDCLRE1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1586569-B1 Aryl ethynyl phthalic acid derivative and method for producing the same FUJIFILM CORP (JP) 2012-06-06 EP disclosed
US-7339071-B2 Aryl ethynyl phthalic acid derivative and method for producing the same FUJIFILM CORPORATION (JP) 2008-03-04 US disclosed
EP-1586569-A1 Aryl ethynyl phthalic acid derivative and method for producing the same FUJI PHOTO FILM CO., LTD. (JP) 2005-10-19 EP disclosed
US-20050215820-A1 Aryl ethynyl phthalic acid derivative and method for producing the same FUJI PHOTO FILM CO., LTD. 2005-09-29 US disclosed