SCHEMBL2747010

SCHEMBL2747010

C#COC(=O)c1ccccc1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.56
ALOX15 P16050 2/20 0.56
NPC1 O15118 1/20 0.48
AKR1C3 P42330 1/20 0.45
KDM4E B2RXH2 4/20 0.43
HPGD P15428 3/20 0.43
HMGB1 P09429 2/20 0.43
NAPRT Q6XQN6 2/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA7 P43166 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
MAPT P10636 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
LMNA P02545 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38734 0.92 NPC1 (0.55) ALDH1A1ALOX15NPC1KDM4EHPGD
SCHEMBL2747742 0.90 ACMSD (0.46) ALDH1A1ALOX15NPC1AKR1C3HPGD
SCHEMBL15537502 0.86 NPC1 (0.41) ALDH1A1ALOX15NPC1AKR1C3KDM4E
SCHEMBL4528196 0.83 HSD17B10 (0.58) ALDH1A1ALOX15NPC1KDM4EHPGD
SCHEMBL2127765 0.82 TSHR (0.55) ALDH1A1ALOX15NPC1KDM4EHPGD
SCHEMBL4578624 0.81 ACMSD (0.51) AKR1C3CDC25BATM
SCHEMBL27888119 0.81 NPC1 (0.46) ALDH1A1ALOX15NPC1KDM4ELMNA
SCHEMBL28310474 0.80 LMNA (0.57) ALDH1A1ALOX15NPC1KDM4EHPGD
SCHEMBL28762966 0.79 BCAT2 (0.52) ALDH1A1HPGDSMN1; SMN2POLBHSD17B10
SCHEMBL2746516 0.77 ALDH1A1 (0.52) ALDH1A1ALOX15NPC1AKR1C3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178631-B2 Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-20090214860-A1 Resin Composition, Varnish, Resin Film and Semiconductor Device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2009-08-27 US disclosed
EP-1953181-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Ltd. (JP) 2008-08-06 EP disclosed
WO-1996024331-A1 NEW MEDICAL FORMS WITH PROLONGED EFFECT APPLIED IN EYE MEDICINE AND THE METHOD FOR PREPARATION THEREOF ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VE^¿D C^¿ESKÉ REPUBLIKY (CZ) 1996-08-15 WO disclosed