SCHEMBL4578726

SCHEMBL4578726

C=Cc1ccccc1CCOC(=O)c1ccc(O)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.40
GCGR P47871 4/20 0.40
CYBB P04839 1/20 0.39
ESR1 P03372 5/20 0.39
ESR2 Q92731 2/20 0.39
KDM4E B2RXH2 1/20 0.37
POLB P06746 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
SERPINE1 P05121 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9556214 0.93 TYR (0.41) TYRL3MBTL1GCGRCYBBESR1
SCHEMBL27981237 0.81 TDP1 (0.53) TYRL3MBTL1ESR1ESR2
SCHEMBL4640396 0.78 THRB (0.43) TYRESR1KDM4EPOLBHDAC6
Ethane SCHEMBL10824994 0.77 CA12 (0.53) TYRESR1KDM4EPOLBHDAC6
SCHEMBL8710748 0.77 SERPINE1 (0.45) GCGRESR1ESR2HSP90AA1HSP90AB1
SCHEMBL4640773 0.74 HDAC6 (0.50) ESR1KDM4EPOLBHDAC6HSP90AA1
SCHEMBL4639808 0.74 HDAC6 (0.47) ESR1KDM4EPOLBHDAC6HSP90AA1
SCHEMBL4577811 0.73 ESR1 (0.40) L3MBTL1GCGRESR1ESR2KDM4E
SCHEMBL4642861 0.73 HDAC6 (0.52) ESR1KDM4EPOLBHDAC6HSP90AA1
SCHEMBL4642799 0.73 HDAC6 (0.52) ESR1KDM4EPOLBHDAC6HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1298490-B1 Photopolymerizable composition and recording material FUJIFILM CORP (JP) 2008-08-13 EP disclosed
US-7399569-B2 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJIFILM CORPORATION (JP) 2008-07-15 US disclosed
EP-1254780-B1 Recording material FUJI PHOTO FILM CO LTD (JP) 2007-01-03 EP disclosed
US-20050187102-A1 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2005-08-25 US disclosed
US-20050158548-A1 Microcapsule, manufacturing method thereof and recording material FUJI PHOTO FILM CO., LTD. 2005-07-21 US disclosed
US-6919159-B2 Photopolymerizable composition and recording material using the same FUJI PHOTO FILM CO., LTD. (JP) 2005-07-19 US disclosed
US-6890879-B2 Recording material and image forming apparatus FUJI PHOTO FILM CO., LTD. (JP) 2005-05-10 US disclosed
US-6846605-B2 Photopolymerizable composition and recording material using same FUJI PHOTO FILM CO., LTD. (JP) 2005-01-25 US disclosed
US-6830861-B2 Photosensitivity; sharp images; high contrast FUJI PHOTO FILM CO., LTD. (JP) 2004-12-14 US disclosed
US-6824953-B2 POLYMERIZABLE COMPOUND HAVING AN ETHYLENIC UNSATURATED BOND, A METHINE DYE, AND A RADICAL GENERATOR THAT INTERACTS WITH THE DYE TO GENERATE A RADICAL FUJI PHOTO FILM CO., LTD. (JP) 2004-11-30 US disclosed
US-20030224294-A1 Photopolymerizable composition and recording material using same FUJIFILM CORPORATION (JP) 2003-12-04 US disclosed
US-20030129521-A1 Photopolymerizable composition and recording material FUJI PHOTO FILM CO., LTD. 2003-07-10 US disclosed
US-20030129523-A1 Photopolymerizable composition and recording material using the same FUJIFILM CORPORATION (JP) 2003-07-10 US disclosed
EP-1298490-A2 Photopolymerizable composition and recording material Fuji Photo Film Co., Ltd. (JP) 2003-04-02 EP disclosed
US-20020182530-A1 Polymerizable compound having an ethylenic unsaturated bond, a methine dye, and a radical generator that interacts with the dye to generate a radical FUJI PHOTO FILM CO., LTD. 2002-12-05 US disclosed
US-20020183202-A1 Recording material and image forming method FUJI PHOTO FILM CO., LTD. 2002-12-05 US disclosed
US-20020168494-A1 Photopolymerizable composition and photosensitive thermal recording material FUJI PHOTO FILM CO., LTD. 2002-11-14 US disclosed
EP-1254780-A2 Recording material and image forming method Fuji Photo Film Co., Ltd. (JP) 2002-11-06 EP disclosed
US-20020142244-A1 Photopolymerizable composition and recording material FUJI PHOTO FILM CO., LTD. 2002-10-03 US disclosed
US-20020051926-A1 Cyanine-based organic dyes, photopolymerizable compositions, and recording materials FUJI PHOTO FILM CO., LTD. (JP) 2002-05-02 US disclosed