Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696866 | 0.86 | TDP1 (0.54) | TDP1LMNATYRESR1ESR2 | |
| SCHEMBL5143591 | 0.84 | PPARG (0.56) | TDP1LMNARAB9AALDH1A1MAPK1 | |
| SCHEMBL29112285 | 0.81 | LMNA (0.46) | TDP1LMNATYRNPC1RAB9A | |
| SCHEMBL8376754 | 0.81 | RAD52 (0.41) | TYRALDH1A1TSHR | |
| SCHEMBL4578726 | 0.81 | TYR (0.48) | TYRESR1ESR2L3MBTL1 | |
| Propene SCHEMBL4012587 | 0.79 | LMNA (0.67) | TDP1LMNAESR1ESR2NPC1 | |
| Propene SCHEMBL6431713 | 0.79 | LMNA (0.67) | TDP1LMNAESR1ESR2NPC1 | |
| Propene SCHEMBL4455281 | 0.79 | LMNA (0.67) | TDP1LMNAESR1ESR2NPC1 | |
| Propene SCHEMBL6062789 | 0.79 | LMNA (0.67) | TDP1LMNAESR1ESR2NPC1 | |
| SCHEMBL6696894 | 0.78 | TDP1 (0.45) | TDP1LMNATYRESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103102264-B | Preparation method of salicylic acid compound | UNIV SICHUAN | 2014-08-20 | — | — | CN | disclosed |